Clinical Focus

  • Cancer > Radiation Oncology
  • Radiation Oncology

Academic Appointments

Professional Education

  • Residency: UCSF Radiation Oncology Residency (1989) CA
  • Internship: St Mary's Medical Center Internal Medicine Residency (1985) CA
  • Medical Education: University of Pennsylvania (1984) PA
  • Board Certification: American Board of Radiology, Radiation Oncology (1989)

Contact

  • Academic
    University - Academic staff Department: Radiation Oncology - Radiation Therapy Position: Clinical Professor
  • Clinical Stanford Cancer Center South Bay 2589 Samaritan Dr San Jose, CA 95124 (669) 233-2164 (fax)
  • Clinical Department of Radiation Oncology 875 Blake Wilbur Dr MC 5847 Stanford, CA 94305 (650) 725-8231 (fax)
  • Clinical Stanford Health Care Radiation Oncology at Pleasanton 5725 W Las Positas Blvd Ste 100B Pleasanton, CA 94588 (925) 660-1166 (fax)

Additional Info

  • Mail Code: 7512

Links

2022-23 Courses

All Publications

  • PSMA- and GRPR-targeted PET: Results from 50 Patients with Biochemically Recurrent Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine Baratto, L., Song, H., Duan, H., Hatami, N., Bagshaw, H., Buyyounouski, M., Hancock, S., Shah, S. A., Srinivas, S., Swift, P., Moradi, F., Davidzon, G. A., Iagaru, A. 2021

    Abstract

    Rationale: Novel radiopharmaceuticals for positron emission tomography (PET) are evaluated for the diagnosis of biochemically recurrent prostate cancer (BCR PC). Here, we compare the gastrin releasing peptide receptors (GRPR) - targeting 68Ga-RM2 with the prostate specific membrane antigen (PSMA) - targeting 68Ga-PSMA11 and 18F-DCFPyL. Methods: Fifty patients had both 68Ga-RM2 PET/MRI and 68Ga-PSMA11 PET/CT (n = 23) or 18F-DCFPyL PET/CT (n = 27) at an interval ranging from 1 to 60 days (mean±SD: 15.8±17.7). Maximum standardized uptake values (SUVmax) were collected for all lesions. Results: RM2 PET was positive in 35 and negative in 15 of the 50 patients. PSMA PET was positive in 37 and negative in 13 of the 50 patients. Both scans detected 70 lesions in 32 patients. Forty-three lesions in 18 patients were identified only on one scan: 68Ga-RM2 detected 7 more lesions in 4 patients, while PSMA detected 36 more lesions in 13 patients. Conclusion: 68Ga-RM2 remains a valuable radiopharmaceutical even when compared with the more widely used 68Ga-PSMA11/18F-DCFPyL in the evaluation of BCR PC. Larger studies are needed to verify that identifying patients for whom these two classes of radiopharmaceuticals are complementary may ultimately allow for personalized medicine.

    View details for DOI 10.2967/jnumed.120.259630

    View details for PubMedID 33674398