
Paul Barry Finn
Basic Life Research Scientist
Bioengineering
Academic Appointments
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Basic Life Science Research Associate, Bioengineering
Honors & Awards
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SPARK Translational Research Program, Stanford SPARK (2020)
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Stanford Alliance for Innovative Medicines (AIM), Stanford ChEM-H & Takeda Pharmaceuticals (2018)
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NIH NRSA Postdoctoral Fellowship, NIH NCI (2017)
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NSF-GK12 Graduate Student Fellowship, NSF (2011)
All Publications
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Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome
PLOS ONE
2020; 15 (12): e0243905
View details for DOI 10.1371/journal.pone.0243905
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Carbocyclic Amino Ketones by Bredt's Rule-Arrested Kulinkovich-de Meijere Reaction
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2016; 55 (7): 2536–39
Abstract
The Ti(II) -mediated formation of cyclopropylamines from alkenes and amides, the Kulinkovich-de Meijere reaction, involves two carbon-carbon bond-forming steps. Strategic use of a tricyclic intermediate can arrest the process if the second step requires formation of a bridgehead double bond. Use of this Bredt's rule constraint results in the production of carbocyclic amino ketones, key alkaloid building blocks.
View details for DOI 10.1002/anie.201509983
View details for Web of Science ID 000369970500044
View details for PubMedID 26840216
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Molecular Recognition of DNA by Py-Im Polyamides: From Discovery to Oncology
DNA-targeting Molecules as Therapeutic Agents
edited by Waring, M. J.
Royal Society of Chemistry. 2018: 298
View details for DOI http://dx.doi.org/10.1039/9781788012928-00298
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Formation and isomerization of polycyclic 1,5-enynes
TETRAHEDRON LETTERS
2015; 56 (23): 3567–70
View details for DOI 10.1016/j.tetlet.2015.01.145
View details for Web of Science ID 000356544800150
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Alpha-amino silanes via metalated imines as an approach to the synthesis of silanediol protease inhibitors
TETRAHEDRON
2013; 69 (36): 7779–84
View details for DOI 10.1016/j.tet.2013.06.022
View details for Web of Science ID 000322939900027