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  • Manganese(II)/Picolinic Acid Catalyst System for Epoxidation of Olefins ORGANIC LETTERS Moretti, R. A., Du Bois, J., Stack, T. D. 2016; 18 (11): 2528-2531

    Abstract

    An in situ generated catalyst system based on Mn(CF3SO3)2, picolinic acid, and peracetic acid converts an extensive scope of olefins to their epoxides at 0 °C in <5 min, with remarkable oxidant efficiency and no evidence of radical behavior. Competition experiments indicate an electrophilic active oxidant, proposed to be a high-valent Mn = O species. Ligand exploration suggests a general ligand sphere motif contributes to effective oxidation. The method is underscored by its simplicity and use of inexpensive reagents to quickly access high value-added products.

    View details for DOI 10.1021/acs.orglett.6b00518

    View details for Web of Science ID 000377319000003

    View details for PubMedID 27191036