Manganese(II)/Picolinic Acid Catalyst System for Epoxidation of Olefins
2016; 18 (11): 2528-2531
An in situ generated catalyst system based on Mn(CF3SO3)2, picolinic acid, and peracetic acid converts an extensive scope of olefins to their epoxides at 0 °C in <5 min, with remarkable oxidant efficiency and no evidence of radical behavior. Competition experiments indicate an electrophilic active oxidant, proposed to be a high-valent Mn = O species. Ligand exploration suggests a general ligand sphere motif contributes to effective oxidation. The method is underscored by its simplicity and use of inexpensive reagents to quickly access high value-added products.
View details for DOI 10.1021/acs.orglett.6b00518
View details for Web of Science ID 000377319000003
View details for PubMedID 27191036