Rouzbeh Fateh, MD

All Publications

• Comparison of sleep quality in women with migraine moreover, multiple sclerosis. Acta medica Iranica Jalilian, R., Ghajarzadeh, M., Fateh, R., Togha, M., Sahraian, M. A., Azimi, A. 2014; 52 (9): 690-3

  Abstract

  Multiple sclerosis (MS) and migraine are two common neurological disorders affecting women more than men. Sleep quality impairment has been reported in both diseases. The goal of this study was to compare sleep quality and depression between women with MS and migraine. Seventy women with migraine and 75 women with MS were enrolled in this study. Participants were asked to fill-out valid and reliable Persian versions of Pittsburg Sleep Questionnaire (PSQI) and Beck Depression Inventory (BDI). Mean age and duration of disease for MS group was 31.1 ± 7.6, 4.8 ± 5 and for second group 31.4 ± 5.6, 5.2 ± 4 years, respectively. Mean BDI score and number of patients with poor sleep (PSQI ≥5) were significantly higher in patients with migraine. There was significant positive correlation between PSQI and BDI scores in all participants (r=0.32, P<0.001), while correlation coefficient was 0.39, P=0.001 in patients with migraine and 0.35, P=0.002 in MS cases. Multiple linear regression analysis between the PSQI as a dependent variable and age, BDI and education level as independent variables showed that BDI is the independent predictors of PSQI in both groups. This study shows that patients with migraine suffer from poor sleep and depression more frequently than MS cases.

  View details for PubMedID 25421842

• Fatigue, depression and sleep disturbances in Iranian patients with multiple sclerosis. Acta medica Iranica Ghajarzadeh, M., Sahraian, M. A., Fateh, R., Daneshmand, A. 2012; 50 (4): 244-9

  Abstract

  Fatigue is one of the most frequent symptoms in patients with multiple sclerosis (MS) and it is difficult to clarify the nature of this symptom and manage it. This study was aimed to evaluate the frequency of fatigue, depression and sleep disturbances in Iranian patients with MS. 100 patients from the outpatient MS clinic of Sina hospital were asked to complete Beck Depression Inventory (BDI), Pittsburg Sleep Quality Index (PSQI), Sleep Disorder Questionnaire (SDQ), Modified Fatigue Impact Scale (MFIS) and Epworth Sleepiness Scale (ESS) questionnaires. Student's t-test, ANOVA, Spearman correlation and Stepwise multiple linear regressions by SPSS version 15.0 were used for data analysis. From participants, 64 had fatigue complaint during day time and 36 did not feel fatigued. BDI, PSQI, MFIS and SDQ scores were significantly higher in fatigued patients than non-fatigued group but there were no statistically significant differences in ESS, EDSS and duration of disease between fatigued and non-fatigued cases. There were significant correlations between MFIS and BDI scores (r=0.49, P=0.01), MFIS and PSQI scores (r=0.399, P=0.01) and MFIS and ESS (r=0.25, P=0.01). This study demonstrates that depression is not the only cause of fatigue in patients with MS and it is also associated with sleep disorders, so this complaint should be carefully evaluated and managed in these patients.

  View details for PubMedID 22592574

• Synbiotic preparation in men suffering from functional constipation: a randomised controlled trial. Swiss medical weekly Fateh, R., Iravani, S., Frootan, M., Rasouli, M. R., Saadat, S. 2011; 141: w13239

  Abstract

  Evaluating the effects of a commercially available synbiotic preparation (contains both prebiotic and probiotic elements) on functional constipation in males.In a randomised controlled trial, a total of 66 adult men with functional constipation were equally allocated to receive a synbiotic mixture or a placebo. The synbiotic mixture or placebo was given as capsules with the same shape and colour, and patients received the capsules twice a day for 4 weeks.A total of 60 patients (31 in the synbiotic group) completed the study. At baseline evaluation, there was no significant difference between the mean stool frequency per week in synbiotic and placebo groups [mean difference of 0.11 times (95% CI: -0.31-0.55), p = 0.58]. However, mean stool frequency increased significantly at weeks 2 [mean difference of 1.32 times (95% CI: 0.21-2.43)] and 4 [mean difference of 1.58 times (95% CI: 0.18-2.99)] in the synbiotic group compared with the placebo group (p = 0.02). A significant difference (p = 0.006) was found at weeks 2 [mean difference of 0.83 (95% CI: 0.20-1.45)] and 4 [mean difference of 0.91 (95% CI: 0.3-1.51)] between the synbiotic and placebo groups regarding the Bristol stool form score. No adverse effect was seen in the synbiotic group.The results of this study indicated that this specific commercial product seemed to be effective in increasing stool frequency and improving consistency in this sample of males with functional constipation. However, further studies with longer follow ups, and including females and elderly patients are required to confirm the efficacy of this product for treatment of functional constipation.

  View details for DOI 10.4414/smw.2011.13239

  View details for PubMedID 21805410

• High rates of psychiatric co-morbidity in individuals with Asperger's disorder. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry Mukaddes, N. M., Fateh, R. 2010; 11 (2 Pt 2): 486-92

  Abstract

  The present study aimed to provide clinical data regarding co-morbidity of psychiatric disorders in individuals diagnosed with Asperger's disorder (AD). This study included 37 individuals (32 male, five female, mean age: 10.9+/-4.5 years) diagnosed with AD. Psychiatric comorbidity was assessed using the Schedule for Affective Disorders and Schizophrenia for School Age Children - Present and Lifetime Version (K-SADS - PL). Ninety-four percent of participants had at least one additional psychiatric disorder. The most common were anxiety disorders (54%), disruptive behavioural disorders (48%), and mood disorders (37%). The results of this study highlight the need for detailed assessment of additional psychiatric disorders in this population.

  View details for DOI 10.1080/15622970902789130

  View details for PubMedID 19347776

• Kleine-Levin syndrome in two subjects with diagnosis of autistic disorder. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry Mukaddes, N. M., Fateh, R., Kilincaslan, A. 2009; 10 (4 Pt 3): 969-72

  Abstract

  Kleine-Levin syndrome (KLS) is a rare disease characterized by recurrent episodes of hypersomnia, cognitive and behavioural disturbances, compulsive eating and hypersexuality. The disease is predominantly described in typically developed adolescents. Here, we present two cases with the diagnosis of KLS and autistic disorder. The aim of this presentation is to illustrate the clinical expression and differential diagnosis of KLS in this group.

  View details for DOI 10.1080/15622970801901810

  View details for PubMedID 18609443