Education & Certifications
M.S., Stanford University, Mechanical Engineering (2021)
B.S., University of Minnesota, Mechanical Engineering (2017)
Post-Baccalaureate Researcher, Los Alamos National Laboratory (June 2018 - August 2019)
Extreme Fluids Team, Physics Division
Los Alamos, NM
The effect of initial conditions on mixing transition of the Richtmyer-Meshkov instability
JOURNAL OF FLUID MECHANICS
View details for DOI 10.1017/jfm.2020.620
View details for Web of Science ID 000575137200001
Termination of Atrial Fibrillation With Epicardial Cooling in the Oblique Sinus.
JACC. Clinical electrophysiology
2018; 4 (10): 1362-1368
This study aimed to determine if epicardial cooling could repeatedly terminate induced atrial fibrillation (AF) in a canine heart.Rapid termination of AF could control symptoms and prevent atrial remodeling; however, defibrillation by internal electrical cardioversion is not tolerable to most patients. Cooling of the epicardium slows atrial conduction and may provide a less painful method to quickly terminate AF.AF was induced with atrial myocardial epinephrine injections and rapid atrial pacing in an open-chest canine. Attempts at termination were performed with a small metal device that was either cooled to 5°C or kept at body temperature (control module). The device was placed on the epicardial surface in the oblique sinus. The time from device contact to termination of AF was recorded.In 5 different canine studies, there were 57 attempts at AF termination with either a 5°C module (34 attempts) or a control module (23 attempts). The median (interquartile range [IQR]) time to AF termination was 24 s (IQR: 15 to 35 s) for the 5°C therapy and 100 s (IQR: 47 to 240 s) for the body temperature treatments (p < 0.001). In the control group, there were 8 AF episodes that continued up to 4 min. Subsequent application of the 5°C cooling module terminated AF in all cases.Epicardial cooling in the oblique sinus is effective for repeated termination of AF in a canine heart. If reproduced in human studies, epicardial cooling with an implantable device may provide a method for management of patients with AF.
View details for DOI 10.1016/j.jacep.2018.06.016
View details for PubMedID 30336883