Professional Education


  • National Post Doctoral Fellow, Indian Institute of Technology, Guwahati, Biotechnology (2019)
  • Ph.D, Brunei Universiti, Biotechnology (2017)
  • Master of Science, Boras University, Industrial Biotechnology (2011)
  • B.Tech, SRM University, Engineering in Biotechnology (2009)

Stanford Advisors


Patents


  • Sharmili Roy. Minhaz Uddin Ahmed. "United States Patent US10889854B2 System and method for immobilization free electrochemiluminescence DNA detection using a luminophore dye for multi-species detection", Universiti Brunei Darussalam, Jan 12, 2021
  • Sharmili Roy, Ibrahim Abdul Rahman, Minhaz Uddin Ahmed. "United States Patent US10465244B2 Electrochemical DNA biosensor using graphene biochip for species identification", Universiti Brunei Darussalam, Nov 5, 2019

All Publications


  • Recent nanobiotechnological advancements in lignocellulosic biomass valorization: A review. Journal of environmental management Roy, S., Dikshit, P. K., Sherpa, K. C., Singh, A., Jacob, S., Chandra Rajak, R. 2021; 297: 113422

    Abstract

    Increase in human population, rapid industrialization, excessive utilization of fossil fuel utilization and anthropogenic activities have caused serious threats to the environment in terms of greenhouse gas emissions (GHGs), global warming, air pollution, acid rain, etc. This destruction in sustainability can be averted by a paradigm shift in the fuel production from fossil resources to bioenergy. Amongst different forms of bioenergy, lignocellulosic biomass can be utilized as an attractive substrate for the production of several high-value products owing to its renewability, easy availability, and abundance. Additionally, utilization of these waste biomasses reduces the environmental hazards associated with its disposal. Impedance of lignin and crystalline nature of cellulose pose major bottlenecks in biomass based energy. Though, several physio-chemicals processes are recommended as mitigation route but none of them seems to be promising for large scale application. In recent years, a right fusion of biological treatment combined with nanotechnology for efficient pretreatment and subsequent hydrolysis of biomass by ubiquitous enzymes seems to be promising alternative. In addition, to overcome these difficulties, nanotechnology-based methods have been recently adopted in catalytic valorization of lignocellulosic biomass. The present review has critically discussed the application of nano-biotechnology in lignocellulosic biomass valorization in terms of pretreatment and hydrolysis. A detailed discussion on the application of various nanoparticles in these processes, enzyme immobilization and end-production utilization is presented in this review. Finally, the review emphasizes the major challenges of this process along with different routes and recommendations to address the issues.

    View details for DOI 10.1016/j.jenvman.2021.113422

    View details for PubMedID 34351298

  • COVID-19 transmission, vulnerability, persistence and nanotherapy: a review. Environmental chemistry letters Khan, A. H., Tirth, V., Fawzy, M., Mahmoud, A. E., Khan, N. A., Ahmed, S., Ali, S. S., Akram, M., Hameed, L., Islam, S., Das, G., Roy, S., Dehghani, M. H. 2021: 1–15

    Abstract

    End 2019,the zoonotic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), named COVID-19 for coronavirus disease 2019, is the third adaptation of a contagious virus following the severe acute respiratory syndrome coronavirus in 2002, SARS-CoV, and the Middle East respiratory syndrome virus in 2012, MERS-CoV. COVID-19 is highly infectious and virulent compared to previous outbreaks. We review sources, contagious routes, preventive measures, pandemic, outbreak, epidemiology of SARS-CoV, MERS-CoV and SARS-CoV-2 from 2002 to 2020 using a Medline search. We discuss the chronology of the three coronaviruses, the vulnerability of healthcare workers, coronaviruses on surface and in wastewater, diagnostics and cures, and measures to prevent spreading.

    View details for DOI 10.1007/s10311-021-01229-4

    View details for PubMedID 33846683

  • Immunotherapeutics for Covid-19 and post vaccination surveillance. 3 Biotech Sampath Kumar, N. S., Chintagunta, A. D., Jeevan Kumar, S. P., Roy, S., Kumar, M. 2020; 10 (12): 527

    Abstract

    Severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged as a pandemic and named as novel coronavirus disease (nCOVID-19). SARS-CoV-2 is different from other known viruses due to multiple mutations on the sites of nonstructural proteins (NSP) 2 and 3, and the varying nature of virulence between different persons. Immunotherapies such as vaccines and monoclonal antibodies have a protective effect on the patients bringing them to the front of the line of potential treatments. The present review intends to cover the development of 20 different vaccine candidates categorized under live attenuated vaccines, inactivated vaccines, subunit vaccines, viral vector-based vaccines, and nucleic acid vaccines. Formulation of these vaccine candidates by various companies in collaboration with global organizations and their status of clinical trials were addressed. On the other hand, various approaches for post-vaccination surveillance using nucleic acid and protein biomarkers imbued on suitable platforms were also highlighted to sum up the immune therapeutics for Covid-19.

    View details for DOI 10.1007/s13205-020-02522-9

    View details for PubMedID 33200061

  • Diverse Molecular Techniques for Early Diagnosis of COVID-19 and Other Coronaviruses Diagnostic Strategies for COVID-19 and other Coronaviruses Roy, S., et al Springer . 2020: 135–159
  • Diagnostic Strategies for COVID-19 and other Coronaviruses Medical Virology: From Pathogenesis to Disease Control edited by Roy, S., et al Springer . 2020
  • Insights into Novel Coronavirus and COVID-19 Outbreak Diagnostic Strategies for COVID-19 and other Coronaviruses Roy, S. Springer . 2020: 1–17