Torsten Joerger, MD, MSCE, is a Clinical Assistant Professor in the Division of Infectious Diseases in the Department of Pediatrics. He serves as the Associate Medical Director of the Antimicrobial Stewardship Program at Stanford Lucile Packard Children’s Hospital. His research interests center around the optimal use of antimicrobials in children as well as clinical epidemiological studies of infections in children.
- Pediatric Infectious Diseases
Clinical Assistant Professor, Pediatrics - Infectious Diseases
Associate Director of Antimicrobial Stewardship, Stanford Lucile Packard Children's Hospital (2021 - Present)
Honors & Awards
Antimicrobial Stewardship Fellow Award, Pediatric Infectious Disease Society (2020)
Boards, Advisory Committees, Professional Organizations
Member, Pediatric Infectious Disease Antimicrobial Stewardship Education Committee (2020 - Present)
Member, Pediatric Infectious Diseases Society (2015 - Present)
Member, Infectious Disease Society of America (2015 - Present)
Residency: Thomas Jefferson University/AI duPont Hospital (2018) DE
Medical Education: Medical College of Wisconsin (2015) WI
MSCE, University of Pennsylvania (2021)
Fellowship: Children's Hospital of Philadelphia Infectious Disease Program (2021) PA
Board Certification: American Board of Pediatrics, Pediatrics (2018)
- Chronic Meningitis Due to Prototheca zopfii in an Adolescent Girl. Journal of the Pediatric Infectious Diseases Society 2021; 10 (3): 370-372
- Treatment-Resistant Bacterial Lymphadenitis in an Otherwise Healthy Girl. Pediatrics in review 2021; 42 (6): 339-341
- Acute, Severe Abdominal Pain in a Non-Sexually Active Adolescent Female. Pediatrics in review 2021; 42 (2): 90-92
Suppurative Intracranial Complications of Pediatric Sinusitis: A Single-Center Experience.
Journal of the Pediatric Infectious Diseases Society
2021; 10 (3): 309-316
Suppurative intracranial complications of sinusitis are rare events in children and can lead to harmful neurologic sequelae and significant morbidity. We sought to review the presentation and management of patients admitted at our hospital with these conditions.This was a retrospective study of pediatric patients admitted to a quaternary children's hospital from 2007 to 2019 for operative management of sinusitis with intracranial extension. Clinical characteristics, including surgical and microbiological data, were collected and analyzed.Fifty-four patients were included; the median age was 11.0 years, and there was a male predominance. Eighty-nine percent of patients had prior healthcare visits for the current episode of sinusitis; 46% of patients had an abnormal neurologic exam on admission. Epidural abscess and subdural empyema were the most common complications, and subdural empyema was associated with repeat surgical intervention. The dominant pathogens were Streptococcus anginosus group organisms (74%). The majority of patients completed treatment parenterally, with a median duration of therapy of 35 days. Neurological sequelae, including epilepsy or ongoing focal deficits, occurred in 22% of patients. History of seizure or an abnormal neurological exam at admission were associated with neurological sequelae.Clinicians should consider intracranial complications of sinusitis in patients with symptoms of sinusitis for >1 week. Patients should undergo urgent neuroimaging, as neurosurgical intervention is essential for these patients. Subdural empyema was associated with repeat neurosurgical intervention. Neurological sequelae occurred in 22% of patients, and new onset seizure or an abnormal neurological exam at admission were associated with neurological sequelae.
View details for DOI 10.1093/jpids/piaa101
View details for PubMedID 32955086
View details for PubMedCentralID PMC8023312
- Impact of an Antimicrobial Stewardship Policy to Restrict Palivizumab Use. Journal of the Pediatric Infectious Diseases Society 2019; 8 (2): 189-190
Murine macrophage inflammatory cytokine production and immune activation in response to Vibrio parahaemolyticus infection.
Microbiology and immunology
2013; 57 (4): 323-8
Vibrio parahaemolyticus is the most common cause of bacterial, seafood-related illness in the USA. Currently, there is a dearth of published reports regarding immunity to infection with this pathogen. Here, production of both pro- and anti-inflammatory cytokines by V. parahaemolyticus-infected RAW 264.7 murine macrophages was studied. It was determined that this infection results in increased concentrations of IL-1α, IL-6, TNF-α and IL-10. Additionally, decreases in cell surface TLR2 and TLR4 and increases in T-cell co-stimulatory molecules CD40 and CD86 were discovered. The data presented here begin to identify the immune variables required to eliminate V. parahaemolyticus from infected host tissues.
View details for DOI 10.1111/1348-0421.12034
View details for PubMedID 23586636
Characterization of Vibrio parahaemolyticus serotype O3:K6 activation of murine macrophage.
AMER ASSOC IMMUNOLOGISTS. 2011
View details for Web of Science ID 000209751704184
Generation of a proinflammatory response by macrophage following infection with an O3:K6 serotype of Vibrio parahaemolyticus
AMER ASSOC IMMUNOLOGISTS. 2010
View details for Web of Science ID 000209758302213
The role of IL-12p40 during host cell infection with Yersinia pestis KIM D27
AMER ASSOC IMMUNOLOGISTS. 2009
View details for Web of Science ID 000209763600389
Disintegrins in health and disease.
Frontiers in bioscience : a journal and virtual library
2008; 13: 6617-37
Few of the proteins isolated and characterized from snake venom have proven to be more chemically diverse, exquisitely specific or promiscuously active than the family known as disintegrins. These small proteins have shown structural homology with hundreds of cell surface molecules from plants and animals other than snakes, and their precise mimicry of native receptor ligands speaks to evolutionary niches related to survival and geographic locale. Over 100 disintegrins have been named and studied, with the most recent efforts into molecular techniques providing significant clues to taxonomic relationships among four different snake families. Investigators have evaluated disintegrin applications in therapies for cancer, asthma, osteopenia and inappropriate angiogenesis. Crystal and NMR studies have confirmed hypotheses regarding ligand-receptor interactions while illuminating the complexities of structure-function evidence. Disintegrin chimeras with viruses, microbubbles and fluorescent labels have become useful tools in many investigations. While many disintegrin studies still involve platelets, previously unexplored interactions with glial cancer, T lymphocytes and the bacteria Yersinia have blazed new trails for this field. This review will summarize disintegrin investigations since 2003.
View details for DOI 10.2741/3177
View details for PubMedID 18508683