Dr. Yoda R. Patta is an Academic Advising Director within the Academic Advising unit of the Office of the Vice Provost for Undergraduate Education (VPUE). She has always had a love of teaching throughout her life and is a dedicated educator and advisor to students. While at MIT, she won the John Wulff Award for Excellence in Teaching and the Goodwin Medal for Excellence in Teaching. Dr. Patta completed her SM and PhD in Materials Science and Engineering at MIT, and became a lecturer there after completing her graduate work.

Dr. Patta holds a patent for a novel method for producing high critical current density superconducting films. Her dissertation work encompassed the bio-distribution of chemotherapeutics delivered via an implantable biocompatible device for the treatment of brain cancer. She went on to complete a postdoc at the Stanford University School of Medicine, where she conducted tissue engineering and wound healing mechanical research.

Current Role at Stanford

Academic Advising Director, Adjunct Professor in Materials Science & Engineering

All Publications

  • The Abnormal Architecture of Healed Diabetic Ulcers is the Result of FAK Degradation by Calpain 1. journal of investigative dermatology Liu, W., Ma, K., Kwon, S. H., Garg, R., Patta, Y. R., Fujiwara, T., Gurtner, G. C. 2017


    Delayed wound healing is a major complication of diabetes occurring in approximately 15% of chronic diabetic patients. It not only significantly affects patients' quality of life but also poses a major economic burden to the health care system. Most efforts have been focused on accelerating wound reepithelialization and closure. However, even after healing the quality of healed tissue in diabetics is abnormal and recurrence is common (50-75%). Thus, understanding how diabetes alters the ultimate mechanical properties of healed wounds will be important to develop more effective approaches for this condition. Focal adhesion kinase is an intracellular protein kinase that plays critical roles in cell migration, focal adhesion formation, and is an important component of cellular mechanotransduction. We have found that focal adhesion kinase expression is downregulated under a high glucose condition both in vitro and in vivo. This is secondary to increased activity of calpain 1, the primary enzyme responsible for focal adhesion kinase degradation, which becomes induced in hyperglycemia. We demonstrate that selective inhibition of calpain 1 activation improves wound healing and normalizes the mechanical properties of diabetic skin, suggesting a new therapeutic approach to prevent diabetic wound recurrence.

    View details for DOI 10.1016/j.jid.2016.11.039

    View details for PubMedID 28082186