Doctor of Philosophy, Weizmann Institute Of Science (2017)
Master of Science, Weizmann Institute Of Science (2012)
Bachelor of Science, Bar-Ilan University (2009)
Current Research and Scholarly Interests
1. Quantum optics of free electrons and light: generation and control of quantum states, quantum measurements and metrology.
2. Optical and electron microscopy: super-resolution, phase microscopy, holography, biological imaging, and quantum enhanced microscopy.
Mark Kasevich, (11/1/2017)
Design for a 10keV multi-pass transmission electron microscope.
2019; 207: 112834
Multi-pass transmission electron microscopy (MPTEM) has been proposed as a way to reduce damage to radiation-sensitive materials. For the field of cryo-electron microscopy (cryo-EM), this would significantly reduce the number of projections needed to create a 3D model and would allow the imaging of lower-contrast, more heterogeneous samples. We have designed a 10keV proof-of-concept MPTEM. The column features fast-switching gated electron mirrors which cause each electron to interrogate the sample multiple times. A linear approximation for the multi-pass contrast transfer function (CTF) is developed to explain how the resolution depends on the number of passes through the sample.
View details for DOI 10.1016/j.ultramic.2019.112834
View details for PubMedID 31520925
- Entangled coherent states created by mixing squeezed vacuum and coherent light OPTICA 2019; 6 (6): 753–57
- Super-resolution enhancement by quantum image scanning microscopy NATURE PHOTONICS 2019; 13 (2): 116-+
- Quantum image scanning microscopy: concept and considerations towards applicability SPIE-INT SOC OPTICAL ENGINEERING. 2019
Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-principle demonstrations. This is primarily due to a combination of low values of fill factors, quantum efficiencies, frame rates and signal-to-noise characteristic of most available single-photon sensitive imaging detectors. Here we describe an imaging device based on a fibre bundle coupled to single-photon avalanche detectors that combines a large fill factor, a high quantum efficiency, a low noise and scalable architecture. Our device enables localization-based super-resolution microscopy in a non-sparse non-stationary scene, utilizing information on the number of active emitters, as gathered from non-classical photon statistics.
View details for DOI 10.1038/ncomms14786
View details for Web of Science ID 000396231500001
View details for PubMedID 28287167
View details for PubMedCentralID PMC5355801
- Quantum enhanced phase retrieval OPTICA 2016; 3 (2): 193-199
- Broadband photon pair generation at 3 omega/2 APPLIED PHYSICS B-LASERS AND OPTICS 2016; 122 (2)
Supersensitive Polarization Microscopy Using NOON States of Light
PHYSICAL REVIEW LETTERS
2014; 112 (10)
A quantum polarized light microscope using entangled NOON states with N=2 and N=3 is shown to provide phase supersensitivity beyond the standard quantum limit. We constructed such a microscope and imaged birefringent objects at a very low light level of 50 photons per pixel, where shot noise seriously hampers classical imaging. The NOON light source is formed by combining a coherent state with parametric down-converted light. We were able to show improved phase images with sensitivity close to the Heisenberg limit.
View details for DOI 10.1103/PhysRevLett.112.103604
View details for Web of Science ID 000332690300009
View details for PubMedID 24679294
Sub-Rayleigh Lithography Using High Flux Loss-Resistant Entangled States of Light
PHYSICAL REVIEW LETTERS
2012; 109 (10)
Quantum lithography achieves phase superresolution using fragile, experimentally challenging entangled states of light. We propose a scalable scheme for creating features narrower than classically achievable with reduced use of quantum resources and, consequently, enhanced resistance to loss. The scheme is an implementation of interferometric lithography using a mixture of a spontaneous parametric down-converted entangled state with intense classical coherent light. We measure coincidences of up to four photons mimicking multiphoton absorption. The results show a narrowing of the interference fringes of up to 30% with respect to the best analogous classical scheme using only 10% of the nonclassical light required for creating NOON states.
View details for DOI 10.1103/PhysRevLett.109.103602
View details for Web of Science ID 000308394900007
View details for PubMedID 23005288
- Experimental tomography of NOON states with large photon numbers PHYSICAL REVIEW A 2012; 85 (2)
Transient Anomalous Diffusion of Telomeres in the Nucleus of Mammalian Cells
PHYSICAL REVIEW LETTERS
2009; 103 (1)
We measured individual trajectories of fluorescently labeled telomeres in the nucleus of eukaryotic cells in the time range of 10(-2)-10(4)sec by combining a few acquisition methods. At short times the motion is subdiffusive with r2 approximately talpha and it changes to normal diffusion at longer times. The short times diffusion may be explained by the reptation model and the transient diffusion is consistent with a model of telomeres that are subject to a local binding mechanism with a wide but finite distribution of waiting times. These findings have important biological implications with respect to the genome organization in the nucleus.
View details for DOI 10.1103/PhysRevLett.103.018102
View details for Web of Science ID 000267697900057
View details for PubMedID 19659180