School of Medicine
Showing 21-40 of 56 Results
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Jennifer Kang
Academic Prog Prof 2, Pediatrics - Infectious Diseases
Current Role at StanfordProgram Manager, Global Child Health Program
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Angelle Desiree LaBeaud
Professor of Pediatrics (Infectious Diseases), Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Epidemiology and Population Health and of Environmental Social Sciences
Current Research and Scholarly InterestsArthropod-borne viruses are emerging and re-emerging infections that are spreading throughout the world. Our laboratory investigates the epidemiology of arboviral infections, focusing on the burden of disease and the long-term complications on human health. In particular, Dr. LaBeaud investigates dengue, chikungunya, and Rift Valley fever viruses in Kenya, where outbreaks cause fever, arthritis, retinitis, encephalitis, and hemorrhagic fever. Our main research questions focus on the risk factors for arboviral infections, the development of diagnostic tests that can be administered in the field to quickly determine what kind of arboviral infection a person has, and the genetic and immunologic investigation of why different people respond differently to the same infection. Our long-term goals are to contribute to a deeper understanding of arboviral infections and their long-term health consequences and to optimize control strategies to prevent these emerging infections. Our laboratory also investigates the effects of antenatal and postnatal parasitic infections on vaccine responses, growth, and development of Kenyan children.
My lab at Stanford supports the field work that is ongoing in Kenya, but we also have several projects that are based locally. We strive to improve diagnostics of arboviral infections and are using Luminex technology to build a new screening assay. We also have created a Luminex based platform to assess vaccine responses against multiple pathogens. -
Grace Lee
Professor of Pediatrics (Infectious Diseases)
BioDr. Grace Lee is Chief Quality Officer and the Christopher G. Dawes Endowed Director of Quality at Stanford Medicine Children’s Health and Lucile Packard Children’s Hospital Stanford, and Associate Dean for Maternal and Child Health (Quality and Safety) and Professor of Pediatrics at Stanford University School of Medicine. She oversees the Center for Pediatric and Maternal Value that seeks to improve quality, safety, patient experience and health equity across the organization. Dr. Lee previously served as a member of the Institute of Medicine Committee (IOM) to Review Priorities in the National Vaccine Plan, the IOM Committee on the Ethical and Scientific Issues in Studying the Safety of Approved Drugs, the National Academies of Sciences, Engineering, and Medicine (NASEM) Committee on Vaccine Research and Development Recommendations for Advancing Pandemic and Seasonal Influenza Preparedness and Response, and AHRQ's Healthcare Safety and Quality Improvement Research Study Section. She also served as a Board Member for the Society for Healthcare Epidemiology of America (SHEA), Pediatric Infectious Diseases Society (PIDS), and the National Academy of Medicine (NAM) Board on Population Health and Public Health Practice. She was previously the Chair of the U.S. Advisory Committee on Immunization Practices (ACIP) that recommends vaccines for the U.S. population, and she is an elected member of the National Academy of Medicine.
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Yvonne Maldonado
Senior Associate Dean, Faculty Development and Diversity, Taube Professor of Global Health and Infectious Diseases, Professor of Pediatrics (Infectious Diseases) and of Epidemiology and Population Health
Current Research and Scholarly InterestsMy research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio. I also work in development of methods to prevent breastfeeding transmission of HIV in Africa.
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Trung Hoang Minh Pham
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsUncovering mechanisms of tissue immunity and immunophysiology during persistent infection
The immune system safeguards the health of complex organisms by rapidly eliminating invading pathogens, curbing infection-induced tissue disruptions, and maintaining tissue homeostasis. Many bacterial pathogens evade host antimicrobial mechanisms and persist in infected tissues at low levels for long periods of time even in the presence of innate and adaptive immune resistance. During persistent infection, the immune system simultaneously orchestrates antimicrobial responses to contain the pathogen, repairs damaged tissue, regulates nutrient resources, and maintains other tissue physiological functions to ensure host survival. Failure of any of these tasks leads to uncontrolled infection, devastating disease, and even death. The goals of our research are to understand:
1)What are the innate and adaptive immune cellular mechanisms that contain pathogens during persistent infection?
2)How are tissue physiological functions, such as tissue repair and nutrient regulation, maintained during persistent infection?
3)How do pathogens survive innate and adaptive antimicrobial mechanisms in infected tissues?
4)How does persistent infection impact host immunity to secondary infections of a similar or different pathogen?
Through investigating these fundamental questions, we may be able to decode the underlying cellular and molecular mechanisms that can be harnessed to eradicate infections, promote tissue resilience, and restore health after an infectious insult. We employ animal infection models and bring together immunology, tissue biology, microbiology, and genetics to uncover the mechanisms of tissue immunity and immunophysiology during persistent infection from the molecular to organismal level.
Current areas of research:
•Development, maintenance, and plasticity of macrophage functional diversity in infected tissue
•Tissue repair and nutrient regulation during persistent infection
•Cellular dynamics and bacterial persistence in lymphoid organs -
Benjamin Pinsky
Professor of Pathology, of Medicine (Infectious Diseases) and, by courtesy, of Pediatrics (Infectious Diseases)
Current Research and Scholarly InterestsDevelopment and application of molecular assays for the diagnosis and management of infectious diseases.