Dr. Teresa Nguyen is a Resident Physician in Anesthesiology at Stanford Medicine. She is passionate about medical innovation and is committed to advancing science education and mentorship. Her research is focused on the intersection of AI and medicine where she studies the applications of large language models in healthcare and subsequent impacts on society. She also mentors students in the Stanford Robotics Team and leads research initiatives for investigating AI-enabled robots' application for improved pediatric care and outcomes. She is the instructor for Chem 93: "Chemistry Unleashed: Exploring the Chemistry that Transforms Our World" at the Stanford Department of Chemistry and is a helicopter pilot.
Dr. Nguyen completed her Bachelor of Science degree in Chemistry at Stanford University, where she was awarded a U.S. Department of State Critical Language Scholarship in Arabic and the Bing Fellowship for her research in Chemistry. She then became a Scientific Researcher at Genentech, where she co-invented and patented a series of drugs for the potential treatment of chronic and neuropathic pain. She attended and received her MD from Stanford University School of Medicine, where she was a Medical Scholars Research Fellow under the mentorship of Professor Carolyn Bertozzi (Nobel laureate in Chemistry 2022). She has published across several medical subspecialties, including head and neck surgery, rhinology, urology, and orthopedic surgery.
Dr. Nguyen is deeply passionate about diversity, equity, and inclusion initiatives. She is the founder of the Lighthouse Initiative, a nonprofit organization whose mission is to provide resources and mentorship to first-generation, low-income, and minority individuals, with a 100% success rate in aiding college admissions for its members. She is also the co-founder of Hands-On Robotics, a nonprofit organization which supports robotics initiatives and education.
- Anesthesiology, Perioperative, and Pain Medicine
Honors & Awards
Critical Language Scholarship - Arabic, United States Department of State
Bing Fellowship, Stanford University Department of Chemistry, Prof. Barry Trost
Medical Scholars, Stanford School of Medicine, Prof. Carolyn Bertozzi (2017)
Medical Doctorate, Stanford University School of Medicine (2020)
Bachelor of Science, Stanford University, Chemistry (2014)
Community and International Work
Hands On Robotics
Opportunities for Student Involvement
The Lighthouse Initiative
Opportunities for Student Involvement
Bergeron, P, Chowdhury, S, Dehnhardt, CM., Focken, T, Grimwood, ME, Hasan, A, Lai, KW, Liu, Z, McKerrall, S, Nguyen, TP, Safina, B, Sutherlin, D, Tan, WT. "United States Patent WO 2017058821 A1 Therapeutic Compounds and Methods Use Thereof", Apr 16, 2017
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain.
Journal of medicinal chemistry
2019; 62 (8): 4091-4109
Using structure- and ligand-based design principles, a novel series of piperidyl chromane arylsulfonamide Nav1.7 inhibitors was discovered. Early optimization focused on improvement of potency through refinement of the low energy ligand conformation and mitigation of high in vivo clearance. An in vitro hepatotoxicity hazard was identified and resolved through optimization of lipophilicity and lipophilic ligand efficiency to arrive at GNE-616 (24), a highly potent, metabolically stable, subtype selective inhibitor of Nav1.7. Compound 24 showed a robust PK/PD response in a Nav1.7-dependent mouse model, and site-directed mutagenesis was used to identify residues critical for the isoform selectivity profile of 24.
View details for DOI 10.1021/acs.jmedchem.9b00141
View details for PubMedID 30943032
Consumption of cruciferous vegetables and the risk of bladder cancer in a prospective US cohort: data from the NIH-AARP diet and health study
AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL UROLOGY
2021; 9 (3): 229-238
View details for Web of Science ID 000672671600004
Hemodynamic changes in patients undergoing office-based sinus procedures under local anesthesia.
International forum of allergy & rhinology
2020; 10 (1): 114–20
The objective of this study is to characterize changes in hemodynamics, pain, and anxiety during office-based endoscopic sinus procedures performed under local anesthesia.We conducted a prospective study of adults undergoing in-office endoscopic sinus procedures under local anesthesia. Patients with American Society of Anesthesiologists (ASA) Physical Status Classification System class 1 or 2 were included. Anesthesia was administered by topical 4% lidocaine/oxymetazoline and submucosal injection of 1% lidocaine/1:200,000 epinephrine. Vital signs and pain were measured at baseline, postinjection, and 5-minute intervals throughout the procedure. Anxiety levels were scored using the State-Trait Anxiety Inventory (STAI). Univariate and multivariate regression analyses were performed to identify factors significantly associated with changes in each hemodynamic metric.Twenty-five patients were studied. This cohort was 52% male, mean age of 57.8 ± 14.4 years, and Charlson Comorbidity Index (CCI) median of 2. Mean procedure duration was 25.0 ± 10.3 minutes. Mean maximal increase in systolic blood pressure (SBP) was 24.6 ± 17.8 mmHg from baseline. Mean maximal heart rate increase was 22.8 ± 10.8 beats per minute (bpm) from baseline. In multivariate regression analysis, when accounting for patient age, cardiac comorbidity, CCI, and ASA, older age was significantly associated with an increase of >20 mmHg in SBP (p = 0.043). Mean pain score during procedures was 1.5 ± 1.3 with a mean maximum of 4.0 ± 2.6. STAI anxiety scores did not change significantly from preprocedure to postprocedure (32.8 ± 11.6 to 31.0 ± 12.6, p = 0.46). No medical complications occurred.Although patients appear to tolerate office procedures well, providers should recognize the potential for significant fluctuations in blood pressure during the procedure, especially in older patients.
View details for DOI 10.1002/alr.22460
View details for PubMedID 31899857
Biomechanical Study of a Multifilament Stainless Steel Cable Crimp System Versus a Multistrand Ultra-High Molecular Weight Polyethylene Polyester Suture Krackow Technique for Achilles Tendon Rupture Repair.
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
2019; 59 (1): 86–90
Currently, Achilles tendon rupture repair is surgically addressed with an open or minimally invasive approach using a heavy, nonabsorbable suture in a locking stitch configuration. However, these sutures have low stiffness and a propensity to stretch, which can result in gapping at the repair site. Our study compares a new multifilament stainless steel cable-crimp repair method to a standard Krackow repair using multistrand, ultra-high molecular weight polyethylene polyester sutures. Eight matched pairs of cadavers were randomly assigned for Achilles tendon repair using either Krackow technique with polyethylene polyester sutures or the multifilament stainless steel cable-crimp technique. Each repair was cyclically loaded from 10 to 50 N for 100 loading cycles, followed by a linear increase in load until complete failure of the repair. During cyclic loading, 4 of the 8 Krackow polyethylene polyester suture repairs failed, whereas none of the multifilament stainless steel cable crimp repairs failed. Load to failure was greater for the multifilament stainless steel cable crimp repairs (321.03 ± 118.71 N) than for the Krackow polyethylene polyester suture repairs (132.47 ± 103.39 N, p = .0078). The ultimate tensile strength of the multifilament stainless steel cable crimp repairs was also greater than that of the Krackow polyethylene polyester suture repairs (485.69 ± 47.93 N vs 378.71 ± 107.23 N, respectively, p = .12). The mode of failure was by suture breakage at the crimp for all cable-crimp repairs and by suture breakage at the knot, within the tendon, or suture pullout for the polyethylene polyester suture repairs. The multifilament stainless steel cable crimp construct may be a better alternative for Achilles tendon rupture repairs.
View details for DOI 10.1053/j.jfas.2019.01.022
View details for PubMedID 31882153
- Budesonide irrigation with olfactory training improves outcomes compared with olfactory training alone in patients with olfactory loss WILEY. 2018: 977–81