Isha Mehrotra

All Publications

• Introduction to Wearable Technology in Arrhythmia Management. Heart rhythm Perez-Guerrero, E. J., Mehrotra, I., Jain, S. S., Perez, M. V. 2024

  View details for DOI 10.1016/j.hrthm.2024.07.098

  View details for PubMedID 39053750

• Large Language Models as Partners in Medical Literature. Heart rhythm Perez-Guerrero, E. J., Mehrotra, I., Jain, S. S., Perez, M. V. 2024

  View details for DOI 10.1016/j.hrthm.2024.07.097

  View details for PubMedID 39053754

• CHARACTERIZING THE GUT MICROBIOTA AND THEIR INTERACTIONS WITH THE HOST IN THE CHRONIC HEART FAILURE-ASSOCIATED ATRIAL FIBRILLATION Mehrotra, I., Snyder, M., Mamic, P. ELSEVIER SCIENCE INC. 2024: 1033

  View details for Web of Science ID 001324901501065

• Survey-Based Study on Food Insecurity During COVID-19 for Households With Children on a Prescribed Gluten-Free Diet. The American journal of gastroenterology Du, N., Mehrotra, I., Weisbrod, V., Regis, S., Silvester, J. A. 2022; 117 (6): 931-934

  Abstract

  Gluten-free (GF) foods are generally costlier than their gluten-containing counterparts. We conducted an anonymous electronic survey to assess food insecurity in households with a child on a prescribed GF diet and how this relates to GF diet adherence during the COVID-19 pandemic. The proportion of households who screened positive using the Hunger Vital Sign was similar to national rates (19%-24%). Approximately 5% of families who screened food secure reported GF food insecurity. Parent-reported intentional gluten consumption due to limited GF food availability in the household increased during the pandemic (7.5%). Food insecurity should be considered in the management of celiac disease.

  View details for DOI 10.14309/ajg.0000000000001778

  View details for PubMedID 35418551

  View details for PubMedCentralID PMC9799129

• Characterization of the blood microbiota in children with Celiac disease. Current research in microbial sciences Mehrotra, I., Serena, G., Cetinbas, M., Kenyon, V., Martin, V. M., Harshman, S. G., Zomorrodi, A. R., Sadreyev, R. I., Fasano, A., Leonard, M. M. 2021; 2: 100069

  Abstract

  Celiac Disease (CD) is an autoimmune disorder triggered by gluten ingestion that can develop in genetically predisposed individuals. Alterations in the gut microbiota have been suggested to contribute to development of autoimmune conditions including CD. Recent work suggests the existence of a blood microbiota. Evidence that alterations in the blood microbiota potentially influence the development of chronic immune based diseases is increasing. However, there is no published literature regarding the blood microbiota in children, including those with CD. This study aimed to characterize the diversity and taxonomic composition of the blood microbiota of children with CD compared to controls. Whole blood samples were collected from children with active CD, CD in remission, and control subjects and 16S rRNA sequencing was utilized to analyze the blood microbiota. We found 16s rRNA present throughout all pediatric blood samples, providing evidence for the presence of a pediatric blood microbiota. We found significant differences in beta diversity and in abundance of certain taxa (Campylobacterales order, Odoribacteraceae and Helicobacteraceae families, Odoribacter genus and species, and Bacteroides acidifaciens species) between subjects with active CD and controls. These taxa have been previously reported to be associated with immune response and gut-inflammatory diseases. We did not find significant differences between subjects with active and remission CD or between remission CD and controls. Conclusions: We provide evidence for a pediatric blood microbiota and identified higher beta diversity and alterations in the composition of blood microbiota in subjects with active CD compared to controls.

  View details for DOI 10.1016/j.crmicr.2021.100069

  View details for PubMedID 34841359

  View details for PubMedCentralID PMC8610358