Clinical Focus


  • Pediatric Hematology-Oncology

Academic Appointments


Professional Education


  • Board Certification: American Board of Pediatrics, Pediatric Hematology-Oncology (2017)
  • Fellowship: Texas Children's Hospital BMT Fellowship Program (2017) TX
  • Fellowship: UC Irvine Pediatric Hematology/Oncology Program (2016) CA
  • Board Certification: American Board of Pediatrics, Pediatrics (2013)
  • Residency: UC Davis Dept of Pediatrics Residency Program (2013) CA
  • Medical Education: Wake Forest University Office of the Registrar (2010) NC

All Publications


  • Strategic infection prevention after genetically modified hematopoietic stem cell therapies: recommendations from the International Society for Cell & Gene Therapy Stem Cell Engineering Committee. Cytotherapy John, T. D., Maron, G., Abraham, A., Bertaina, A., Bhoopalan, S. V., Bidgoli, A., Bonfim, C., Coleman, Z., DeZern, A., Li, J., Louis, C., Oved, J., Pavel-Dinu, M., Purtill, D., Ruggeri, A., Russell, A., Wynn, R., Boelens, J. J., Prockop, S., Sharma, A. 2024

    Abstract

    There is lack of guidance for immune monitoring and infection prevention after administration of ex vivo genetically modified hematopoietic stem cell therapies (GMHSCT). We reviewed current infection prevention practices as reported by providers experienced with GMHSCTs across North America and Europe, and assessed potential immunologic compromise associated with the therapeutic process of GMHSCTs described to date. Based on these assessments, and with consensus from members of the International Society for Cell & Gene Therapy (ISCT) Stem Cell Engineering Committee, we propose risk-adapted recommendations for immune monitoring, infection surveillance and prophylaxis, and revaccination after receipt of GMHSCTs. Disease-specific and GMHSCT-specific considerations should guide decision making for each therapy.

    View details for DOI 10.1016/j.jcyt.2024.02.005

    View details for PubMedID 38483362

  • Red Cell Rheology and Blood Viscosity in Pediatric Individuals Having Received Allogenic Hematopoietic Stem Cell Transplantation or Ex Vivo Autologous Gene Therapy for Sickle Cell Disease Patel, A. P., Kanne, C. K., Stenger, E. O., John, T. D., Sheehan, V. A. AMER SOC HEMATOLOGY. 2023
  • Regimen Intensity and Age Affect Transplant-Related Outcomes after Matched Related Donor Hematopoietic Cell Transplantation for Sickle Cell Disease: A STAR Registry Study John, T. D., Chellapandian, D., Shah, R., Gillespie, S., Liu, K., Xiang, Y., Bhatia, M., Chaudhury, S., Eckrich, M. J., Guilcher, G. T., Jaroscak, J., Kasow, K. A., Krajewski, J., Ngwube, A. I., Olson, T. S., Rangarajan, H. G., Horan, J. T., Krishnamurti, L., Shenoy, S., Abraham, A., Stenger, E. AMER SOC HEMATOLOGY. 2023
  • Donor Hemoglobin Genotype Does Not Impact Outcomes Following Matched Related Donor Hematopoietic Cell Transplantation for Sickle Cell Disease: A STAR Study Stenger, E., John, T. D., Chellapandian, D., Shah, R., Gillespie, S., Xiang, Y., Liu, K., Bhatia, M., Guilcher, G. T., Jaroscak, J., Kasow, K. A., Krajewski, J., Ngwube, A. I., Rangarajan, H. G., Horan, J. T., Krishnamurti, L., Shenoy, S., Abraham, A. AMER SOC HEMATOLOGY. 2023