Jenny Woo

All Publications

• Peripheral Vascular Calcification. Arteriosclerosis, thrombosis, and vascular biology Lee, S., Woo, J., Chen, Y., Arya, S., Allison, M. 2026

  Abstract

  Peripheral artery disease commonly refers to diffuse atherothrombotic disease of the arteries supplying the legs. Peripheral artery disease has been relatively understudied and has not been subject to the same intensive scrutiny and research that characterizes coronary artery disease. Moreover, the diagnosis of peripheral artery disease can be complicated by the presence of arterial calcification. Here, we provide a brief report on the current understanding of peripheral vascular calcification to include the following sections: basic mechanisms, anatomic distribution of arterial calcification, manifestations, risk factors, measurement of peripheral calcification, nonsurgical treatments, and surgical interventions.

  View details for DOI 10.1161/ATVBAHA.125.322138

  View details for PubMedID 41537264

  View details for PubMedCentralID PMC12810862

• Quantification of arterial calcification in peripheral artery disease and its association with amputation and/or mortality: A systematic review. Vascular medicine (London, England) Woo, J., Fereydooni, A., Patel, J., Lakshmi, A., Lee, S., Trickey, A., Arya, S. 2025: 1358863X251334572

  Abstract

  Arterial calcification is prevalent in peripheral artery disease (PAD), especially among patients with advanced age, diabetes, or renal disease. Peripheral arterial calcium score (PACS) is an emerging tool to quantify calcification in peripheral arteries and predict outcomes such as amputation and mortality. This systematic review evaluates PACS methodologies and its association with these adverse outcomes. In a comprehensive search of Embase, MEDLINE, and PubMed from January 1991 to January 2025, 1092 studies were retrieved, of which 17 met the inclusion criteria. Computed tomography and X-ray imaging were the main imaging modalities used to detect calcification through a variety of PACS. A higher PACS was linked to increased risk of amputation and/or mortality. PACS holds potential for predicting outcomes in PAD, particularly amputation and mortality. Standardization of PACS methods is needed to enhance its clinical utility and integration into practice.

  View details for DOI 10.1177/1358863X251334572

  View details for PubMedID 40366061

• Early identification and treatment of women's cardiovascular risk factors prevents cardiovascular disease, saves lives, and protects future generations: Policy recommendations and take action plan utilizing policy levers CLINICAL CARDIOLOGY Ivey, S. L., Hanley, H., Taylor, C., Stock, E., Vora, N., Woo, J., Johnson, S., Merz, C., Right Care Womens Cardiovasc Writi 2022

  Abstract

  Cardiovascular diseases (CVD) including heart attacks, strokes, heart failure, and uncontrolled hypertension are leading causes of death among women of all ages. Despite efforts to increase awareness about CVD among women, over the past decade there has been stagnation in the reduction of CVD in women, and CVD among younger women and women of color has in fact increased. We recommend taking action using policy levers to address CVD in women including: (1) Promoting periodic screening for risk factors including blood pressure, lipids/cholesterol, diabetes for all women starting at 18-21 years, with calculated atherosclerotic CVD (ASCVD) risk score use among women 40 years or older. (2) Considering coronary artery calcium (CAC) screening for those with intermediate risk per current guidelines. (3) Enhancing Obstetrics and Gynecology and primary care physician education on reproductive age CVD risk markers, and that follow-up is needed, including extended postpartum follow-up. (4) Offering Health Coaching/motivational Interviewing to support behavior change. (5) Funding demonstration projects using different care models. (6) Creating a Stop High Blood Pressure consult line (for providers and patients) and providing other support resources with actions consumers can take, modeled after the California tobacco quit line. And (7) Requiring inclusion of adverse pregnancy outcomes in all Electronic Health Records, with reminder systems to follow-up on hypertension post-partum.

  View details for DOI 10.1002/clc.23921

  View details for Web of Science ID 000855725000001

  View details for PubMedID 36128629