Contact

  • Academic
    amcarter@stanford.edu
    University - Student Department: Microbiology and Immunology Position: Graduate

All Publications

  • Chemical strategies for targeting lipid pathways in bacterial pathogens. Current opinion in chemical biology Carter, A. M., Woods, E. C., Bogyo, M. 2025; 86: 102596

    Abstract

    Microbial pathogens continue to plague human health and develop resistance to our current frontline treatments. Over the last few decades, there has been limited development of antibiotics with new mechanisms of action, highlighting our need to identify processes that can be targeted by next generation therapeutics. Recent advancements in our understanding of the roles that lipids play in key bacterial processes suggest that these biomolecules are a potentially valuable site for disruption by therapeutic agents. Specifically, the success of a pathogen depends on its ability to make fatty acids de novo or scavenge lipids from its host. This review focuses on recent advances using chemical biology tools for defining and disrupting lipid pathways in bacteria.

    View details for DOI 10.1016/j.cbpa.2025.102596

    View details for PubMedID 40253721