Clinical Focus


  • Anesthesia

Academic Appointments


Honors & Awards


  • H. B. Fairley Teaching Excellence Award, Department of Anesthesiology, Perioperative and Pain Medicine (2019)

Professional Education


  • Board Certification: American Board of Anesthesiology, Anesthesia (2017)
  • Fellowship: Stanford University Anesthesiology Fellowships (2017) CA
  • Residency: Stanford University Anesthesiology Residency (2016) CA
  • Internship: Stanford University Internal Medicine Residency (2013) CA
  • M. D., David Geffen School of Medicine at UCLA (2012)
  • B. S., Massachusetts Institute of Technology, Materials Science & Engineering (2007)

Current Research and Scholarly Interests


Head & Neck Anesthesia
Advanced Airway Management
Anesthesia for Adults with Epidermolysis Bullosa

All Publications


  • The Safety and Efficacy of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange for Laryngologic Surgery. The Laryngoscope Nekhendzy, V. n., Saxena, A. n., Mittal, B. n., Sun, E. n., Sung, K. n., Dewan, K. n., Damrose, E. J. 2020

    Abstract

    Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) is an intraoperative ventilatory technique that allows avoidance of tracheal intubation (TI) or jet ventilation (JV) in selected laryngologic surgical cases. Unimpeded access to all parts of the glottis may improve surgical precision, decrease operative time, and potentially improve patient outcomes. The objective of this prospective, randomized, patient-blinded, 2-arm parallel pilot trial was to investigate the safety and efficacy of THRIVE use for adult patients undergoing nonlaser laryngologic surgery of short-to-intermediate duration.Twenty adult, American society of anesthesiology class 1-3 patients with body mass index (BMI) < 35 kg/m2 were randomly assigned to either an experimental THRIVE group or active comparator conventional ventilation group (TI or supraglottic high-frequency JV [SHFJV]). Primary outcomes included intraoperative oxygenation, anesthesia awakening/extubation time, time to laryngoscopic suspension, number of intraoperative suspension adjustments, and operative time. Secondary patient outcomes including postanesthesia and functional patient recovery were investigated.Compared to TI/SHFJV, THRIVE use was associated with significantly lower intraoperative oxygenation (SpO2 93.0 ± 5.6% vs. 98.7 ± 1.6%), shorter time to suspension (1.8 ± 1.1 minutes vs. 4.3 ± 2.1 minutes), fewer suspension adjustments (0.4 ± 0.5 vs. 1.7 ± 0.9), and lower postoperative pain scores on recovery room admission (1.3 ± 1.9 vs. 3.7 ± 2.9) and discharge (0.9 ± 1.3 vs. 2.7 ± 1.8). The study was underpowered to detect other possible outcome differences.We confirm the safe intraoperative oxygenation profile of THRIVE for selected patients undergoing nonlaser laryngologic surgery of short-to-intermediate duration. THRIVE facilitated surgical exposure and improved early patient recovery, suggesting a potential economic benefit for outpatient laryngologic procedures. The results of this exploratory study provide a framework for designing future adequately powered THRIVE trials.ClinicalTrials.gov (NCT03091179).II Laryngoscope, 2020.

    View details for DOI 10.1002/lary.28562

    View details for PubMedID 32078170