Bio-X
Showing 41-50 of 93 Results
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Carolyn Bertozzi
Baker Family Director of Sarafan ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology and of Radiology
BioProfessor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.
Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosaccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford University in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering & Medicine for Human Health). She is now the Baker Family Director of Stanford ChEM-H.
Named a MacArthur Fellow in 1999, Dr. Bertozzi has received many awards for her dedication to chemistry, and to training a new generation of scientists fluent in both chemistry and biology. She has been elected to the Institute of Medicine, National Academy of Sciences, and American Academy of Arts and Sciences; and received the Lemelson-MIT Prize, the Heinrich Wieland Prize, the ACS Award in Pure Chemistry, and the Chemistry of the Future Solvay Prize, among others.
The Bertozzi Group develops chemical tools to study the glycobiology underlying diseases such as cancer, inflammation, tuberculosis and most recently COVID-19. She is the inventor of "bioorthogonal chemistry", a class of chemical reactions compatible with living systems that enable molecular imaging and drug targeting. Her group also developed new therapeutic modalities for targeted degradation of extracellular biomolecules, such as antibody-enzyme conjugates and Lysosome Targeting Chimeras (LYTACs). As well, her group studies NGly1 deficiency, a rare genetic disease characterized by loss of the human N-glycanase.
Several of the technologies developed in the Bertozzi lab have been adapted for commercial use. Actively engaged with several biotechnology start-ups, Dr. Bertozzi cofounded Redwood Bioscience, Enable Biosciences, Palleon Pharmaceuticals, InterVenn Bio, OliLux Bio, Grace Science LLC and Lycia Therapeutics. She is also a member of the Board of Directors of Lilly. -
Vivek Bhalla, MD
Associate Professor of Medicine (Nephrology)
On Partial Leave from 03/01/2024 To 08/31/2024Current Research and Scholarly InterestsDr. Bhalla's two primary research interests are in the role of the kidney in diabetes and hypertension. We use molecular, biochemical, and transgenic approaches to study: (1) mechanisms diabetic kidney disease disease including the role of the endothelium to regulate inflammation and kidney injury; and (2) regulation of tubular transport of glucose, sodium, and potassium. These latter studies have treatment implications in diabetes, kidney disease, and hypertension.
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Ami Bhatt
Associate Professor of Medicine (Hematology) and of Genetics
Current Research and Scholarly InterestsThe Bhatt lab is exploring how the microbiota is intertwined with states of health and disease. We apply the most modern genetic tools in an effort to deconvolute the mechanism of human diseases.
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Nidhi Bhutani
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsThe long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease.
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Lacramioara Bintu
Assistant Professor of Bioengineering
BioLacra Bintu is an Assistant Professor in the Bioengineering Department at Stanford. Her lab performs single-cell and high-throughput measurements of chromatin and gene regulation dynamics, and uses these data to develop predictive models and improve mammalian cell engineering.
Lacra started working on the theory of gene regulation as an undergraduate with Jané Kondev from Brandeis University and Rob Phillips from Caltech. As a Physics PhD student in the lab of Carlos Bustamante at U.C. Berkeley, she used single-molecule methods to tease apart the molecular mechanisms of transcription through nucleosomes. She transitioned to studying the dynamics of epigenetic regulation in live cells during her postdoctoral fellowship with Michael Elowitz at Caltech. -
Biondo Biondi
Barney and Estelle Morris Professor
On Leave from 09/01/2023 To 08/31/2024Current Research and Scholarly InterestsResearch
My students and I devise new algorithms to improve the imaging of reflection seismic data. Images obtained from seismic data are the main source of information on the structural and stratigraphic complexities in Earth's subsurface. These images are constructed by processing seismic wavefields recorded at the surface of Earth and generated by either active-source experiments (reflection data), or by far-away earthquakes (teleseismic data). The high-resolution and fidelity of 3-D reflection-seismic images enables oil companies to drill with high accuracy for hydrocarbon reservoirs that are buried under two kilometers of water and up to 15 kilometers of sediments and hard rock. To achieve this technological feat, the recorded data must be processed employing advanced mathematical algorithms that harness the power of huge computational resources. To demonstrate the advantages of our new methods, we process 3D field data on our parallel cluster running several hundreds of processors.
Teaching
I teach a course on seismic imaging for graduate students in geophysics and in the other departments of the School of Earth Sciences. I run a research graduate seminar every quarter of the year. This year I will be teaching a one-day short course in 30 cities around the world as the SEG/EAGE Distinguished Instructor Short Course, the most important educational outreach program of these two societies.
Professional Activities
2007 SEG/EAGE Distinguished Instructor Short Course (2007); co-director, Stanford Exploration Project (1998-present); founding member, Editorial Board of SIAM Journal on Imaging Sciences (2007-present); member, SEG Research Committee (1996-present); chairman, SEG/EAGE Summer Research Workshop (2006) -
Julius Bishop, MD
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Bishop specializes in treating fractures of the upper extremity, lower extremity, pelvis and acetabulum as well as the management of post-traumatic problems including malunion, nonunion and infection.
He received his undergraduate and medical school degrees from Harvard University and went on to complete the Harvard Combined Orthopaedic Surgery Residency Program. He pursued his subspecialty training in Orthopaedic Traumatology at the world-renowned Harborview Medical Center in Seattle, Washington.
His research interests include applying decision analysis models to orthopaedic trauma problems, studying clinical outcomes after musculoskeletal injury, orthopaedic biomechanics, the basic science of fracture healing, and evaluating new strategies and techniques in fracture surgery. -
Sandip Biswal, MD
Adjunct Clinical Professor, Radiology
Current Research and Scholarly InterestsThe management of individuals suffering from chronic pain is unfortunately limited by poor diagnostic tests and therapies. Our research group is interested in 'imaging pain' by using novel imaging techniques to study peripheral nociception and inflammation with the goal of accurately identifying the location of pain generators. We are developing new approaches with positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) and are currently in clinical trials.
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Helen M. Blau
Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
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Nikolas Blevins, MD
Larry and Sharon Malcolmson Professor in the School of Medicine, Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsInner ear microendoscopy -- Developing techniques for minimally-invasive imaging of inner ear microanatomy and neural pysiology. Applications include improved cochlear implant development, inner ear regenerative techniques, inner ear surgery, and auditory physiology.
Microsurgical robotics -- Developing scalable microsurgical instrumentation and robotic techniques for use in head and neck surgery.
Surgical Simulation -- Immersive environment for temporal bone surgical simulation.