School of Engineering
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Matteo Cargnello
Associate Professor of Chemical Engineering
BioMatteo Cargnello received his Ph.D. in Nanotechnology in 2012 at the University of Trieste, Italy, under the supervision of Prof. Paolo Fornasiero, and he was then a post-doctoral scholar in the Chemistry Department at the University of Pennsylvania with Prof. Christopher B. Murray before joining the Faculty at Stanford University in January 2015. He is currently Associate Professor of Chemical Engineering and, by courtesy, of Materials Science and Engineering and Vance D. and Arlene C. Coffman Faculty Scholar. Dr. Cargnello is the recipient of several awards including the Sloan Fellowship in 2018, the Mitsui Chemicals Catalysis Science Award for Creative Work in 2020, and the Early Career Award in Catalysis from the ACS Catalysis Division in 2022. The general goals of the research in the Cargnello group pertain to solving energy and environmental challenges. The group focuses on capture and conversion of carbon dioxide, emission control and reduction of methane and hydrocarbon emissions in the atmosphere, sustainable chemical practices through electro- and photocatalysis, sustainable production of hydrogen, and chemical recycling of plastics.
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Lynette Cegelski
Associate Professor of Chemistry and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsOur research program is inspired by the challenge and importance of elucidating chemical structure and function in complex biological systems and the need for new strategies to treat infectious diseases. The genomics and proteomics revolutions have been enormously successful in generating crucial "parts lists" for biological systems. Yet, for many fascinating systems, formidable challenges exist in building complete descriptions of how the parts function and assemble into macromolecular complexes and whole-cell factories. We have introduced uniquely enabling problem-solving approaches integrating solid-state NMR spectroscopy with microscopy and biochemical and biophysical tools to determine atomic- and molecular-level detail in complex macromolecular assemblies and whole cells and biofilms. We are uncovering new chemistry and new chemical structures produced in nature. We identify small molecules that influence bacterial assembly processes and use these in chemical genetics approaches to learn about bacterial cell wall, amyloid and biofilm assembly.
Translationally, we have launched a collaborative antibacterial drug design program integrating synthesis, chemical biology, and mechanistic biochemistry and biophysics directed at the discovery and development of new antibacterial therapeutics targeting difficult-to-treat bacteria.
