Natural Sciences
Showing 641-660 of 696 Results
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Virginia Walbot
Professor of Biology, Emerita
Current Research and Scholarly InterestsOur current focus is on maize anther development to understand how cell fate is specified. We discovered that hypoxia triggers specification of the archesporial (pre-meiotic) cells, and that these cells secrete a small protein MAC1 that patterns the adjacent soma to differentiate as endothecial and secondary parietal cell types. We also discovered a novel class of small RNA: 21-nt and 24-nt phasiRNAs that are exceptionally abundant in anthers and exhibit strict spatiotemporal dynamics.
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Li Wang
Assistant Professor of Biology
Current Research and Scholarly InterestsWe study how the extraordinary diversity of cells and synapses in the brain is generated, organized, and maintained, and how these processes are disrupted in diseases such as neurodevelopmental disorders and brain cancer. By combining single-cell and spatial genomics, lineage tracing, perturbation screens, synaptic proteomics, and machine learning models, we aim to uncover the molecular rules that define neural identity and connectivity.
Our research spans two interrelated themes, each grounded in human biology and driven by cutting-edge technologies. By comparing these processes across species, we aim to uncover both conserved mechanisms and human-specific innovations that define the unique features of the human brain. -
Dr. Zhiyong Wang
Professor (By Courtesy), Biology
BioDr. Wang is the acting director of the Department of Plant Biology, Carnegie Institution for Science, and a professor by courtesy of the Department of Biology, Stanford University. He is currently an associate editor of Molecular Cellular Proteomics, and editorial board member of Molecular Plant. He is a Fellow of the American Association for the Advancement of Science (AAAS) and recipient of the Humboldt Research Prize.
Dr. Wang obtained his Ph.D. in 1998 from UCLA, where he cloned the plant circadian clock gene CCA1. He did his postdoctoral research at the Salk Institute, where he studied the brassinosteroid signaling mechanism mediated by the BRI1 receptor kinase. Since joining Carnegie in 2001, his research has illustrated the receptor kinase signaling pathway that links the BRI1 receptor kinase to the BZR1 transcription factor and brassinosteroid-responsive genes in the Arabidopsis genome. He further demonstrated how the steroid signaling pathway integrates at the molecular level with other hormonal pathways, light signaling pathways, nutrient-sensing pathways, immunity pathways, and the circadian clock, to coordinately regulate plant growth and development. His lab uses combinations of genomic and proteomic approaches to understand how cellular signals are transduced and integrated through posttranslational modifications (e.g. phosphorylation and O-Glycosylation) and protein-protein interactions. His studies are elucidating the molecular mechanisms that control plant growth and mediate responses to environmental changes. -
Ward Watt
Professor, Biology
Current Research and Scholarly InterestsEvolutionary adaptive mechanisms, molecules to ecosystems
