School of Humanities and Sciences
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Christopher O. Barnes
Assistant Professor of Biology and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsResearch in our lab is aimed at defining the structural correlates of broad and potent antibody-mediated neutralization of viruses. We combine biophysical and structural methods (e.g., cryo-EM), protein engineering, and in vivo approaches to understand how enveloped viruses infect host cells and elicit antigen-specific immune responses. We are particularly interested in the co-evolution of HIV-1 and broadly-neutralizing IgG antibodies (bNAbs), which may hold the key to the development of an effective HIV-1 vaccine. In addition, we are investigating antibody responses to SARS-CoV-2 and related zoonotic coronaviruses (CoV), with the related goal of developing broadly-protective immunotherapies and vaccines against variants of concern and emerging CoV threats.
HIV-1; SARS-CoV-2; coronaviruses; cryo-EM; crystallography; vaccines; directed evolution
Associate Professor, Biology
Consulting Professor, Biology
Current Research and Scholarly InterestsPlants make new leaves and stems from clusters of undifferentiated cells located at the tips of branches. These cell clusters are called apical meristems. We study transcription factors that control growth and development of apical meristems. Our studies include plants growing in environments rich in water and nutrients as well as in poor environments. The deeper knowledge of plant development gained from these studies will ultimately help increase food security in a changing environment.
Shirley R. and Leonard W. Ely, Jr. Professor of the School of Humanities and Sciences
Current Research and Scholarly InterestsWe use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division.
Charles and Elizabeth Prothro Professor of Marine Sciences, Professor of Oceans and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsThermal physiology, open ocean predators, ecological physiology and tuna biology
Bing Director in Human Biology, Emerita
Current Research and Scholarly InterestsI am interested in how environmental variation affects life history traits, population structure and dynamics, and species interactions in ecological and evolutionary time, using Lepidoptera.
Assist Prof (By Courtesy), Biology
BioAdrien Burlacot is an algal physiologist specialized in the study of photosynthesis and bioenergetics of algal cell. Adrien is a physicist by training, he received a BS and MSc in Engineering from the Ecole polytechnique (France) and a MSc in Plant Biology from the University of Paris-Saclay (France). He then obtained a PhD in Plant Science at the CEA Cadarache (France) from the Aix-Marseille University (France) where he studied the regulations of the photosynthetic electron flow in green microalgae. After a postdoctoral position in 2021 at the University of California, Berkeley (USA) with Krishna K. Niyogi were he studied photoprotection in plants and algae, he started his lab at the Carnegie Institution for Science at Stanford on fall 2021.
Microalgal photosynthesis is fixing annually ten times more CO2 than what humans reject. Acclimation to abiotic stress is a major driving force of microalgal community structure and productivity. Adrien investigates how microalgal photosynthesis dynamically acclimates to fluctuations in environmental parameters like light, CO2 or temperature. He will be using and developing high throughput screens based on quantitative chlorophyll fluorescence to understand the dynamics of photosynthesis. Adrien aims at unravelling the network of photosynthesis acclimatory genes and their bioenergetic role in the cell. He wants to use this knowledge and the new tools developed to propose new ways of harnessing photosynthesis for a more sustainable world.