School of Humanities and Sciences
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Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology and of Radiology
BioProfessor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.
Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosaccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford University in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering & Medicine for Human Health). She is now the Baker Family Director of Stanford ChEM-H.
Named a MacArthur Fellow in 1999, Dr. Bertozzi has received many awards for her dedication to chemistry, and to training a new generation of scientists fluent in both chemistry and biology. She has been elected to the Institute of Medicine, National Academy of Sciences, and American Academy of Arts and Sciences; and received the Lemelson-MIT Prize, the Heinrich Wieland Prize, the ACS Award in Pure Chemistry, and the Chemistry of the Future Solvay Prize, among others.
The Bertozzi Group develops chemical tools to study the glycobiology underlying diseases such as cancer, inflammation, tuberculosis and most recently COVID-19. She is the inventor of "bioorthogonal chemistry", a class of chemical reactions compatible with living systems that enable molecular imaging and drug targeting. Her group also developed new therapeutic modalities for targeted degradation of extracellular biomolecules, such as antibody-enzyme conjugates and Lysosome Targeting Chimeras (LYTACs). As well, her group studies NGly1 deficiency, a rare genetic disease characterized by loss of the human N-glycanase.
Several of the technologies developed in the Bertozzi lab have been adapted for commercial use. Actively engaged with several biotechnology start-ups, Dr. Bertozzi cofounded Redwood Bioscience, Enable Biosciences, Palleon Pharmaceuticals, InterVenn Bio, OliLux Bio, Grace Science LLC and Lycia Therapeutics. She is also a member of the Board of Directors of Lilly.
Roshan Ganesh Bhaskar
Ph.D. Student in Chemistry, admitted Autumn 2019
BioGraduate Student: Department of Chemistry, Stanford University.
Undergraduate Studies: BA Biochemistry, Columbia University
Postdoctoral Scholar, Chemistry
BioAhanjit Bhattacharya is a postdoctoral researcher in the lab of Steven Boxer at the Department of Chemistry. His core philosophy of research is "learning through building". Ahanjit carried out his doctoral research at the University of California San Diego. He worked on designing artificial cellular systems from fundamental building blocks. He also has a deep interest in understanding the origins and evolution of life. Ahanjit's major accomplishments are development of lipid compartments as programmable synthetic cells and organelles, and development of minimal biochemical strategies for synthesis of membrane-forming lipids. His experience with lipid materials inspired him to gain expertise in the area of membrane biophysics. Currently, Ahanjit is working on physical mechanisms of fusion of enveloped viruses with lipid membranes. He is also trying to understand structure-function relationships in complex archaeal lipids. He uses a host of biophysical tools which includes X-ray scattering, single particle microscopy, and electron microscopy. Ahanjit is passionate about communicating science and making it a transformational force for betterment of society and humanity.
Camille Dreyfus Professor of Chemistry
Current Research and Scholarly InterestsPlease visit my website for complete information:
J.G. Jackson and C.J. Wood Professor of Chemistry, Emeritus
BioJohn Brauman’s research has advanced the understanding of the factors that determine the rates and products of chemical reactions. His primary areas of effort have involved the spectroscopy, photochemistry, reaction dynamics, and reaction mechanisms of gas-phase ions.
John I. Brauman was born in Pittsburgh, PA in 1937. He attended the Massachusetts Institute of Technology (S.B. 1959) and the University of California at Berkeley (Ph.D. 1963). Following a National Science Foundation Postdoctoral Fellowship at the University of California, Los Angeles, he accepted a position at Stanford University where he is now J. G. Jackson - C. J. Wood Professor of Chemistry Emeritus, and serves as Associate Dean of Research. He was previously Department Chair and Associate Dean for Natural Sciences.
Brauman’s work has been recognized in the National Medal of Science, National Academy of Sciences Award in Chemical Sciences, Linus Pauling Medal, Dean's Award for Distinguished Teaching from Stanford University, among many other honors. He is a member of the National Academy of Sciences, American Academy of Arts and Sciences, American Philosophical Society, a Fellow of the American Association for the Advancement of Science, Fellow of the American Chemical Society, and Honorary Fellow of the California Academy of Sciences. He received the 2017 ACS Parsons Award in recognition of his service to public science communication and policy, which includes roles as Deputy Editor for Physical Sciences and Editorial Board Chair for Science magazine, and Home Secretary of the National Academy of Sciences.
Research in the Brauman Group centered on structure and reactivity. Brauman has studied ionic reactions in the gas phase, including acid-base chemistry, the mechanisms of proton transfers, nucleophilic displacement, and addition-elimination reactions. His work has explored the shape of the potential surfaces and the dynamics of reactions on these surfaces. He has made contributions to the field of electron photodetachment spectroscopy of negative ions, measurements of electron affinities, the study of dipole-supported electronic states, and multiple photon infrared activation of ions. He has also studied mechanisms of solution and gas phase organic reactions as well as organometallic reactions and the behavior of biomimetic organometallic species.