School of Medicine
Showing 3,551-3,560 of 5,026 Results
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Carla Pugh, MD, PhD
Thomas Krummel Professor
Current Research and Scholarly InterestsThe Technology Enabled Clinical Improvement (T.E.C.I.) Center is a multidisciplinary team of researchers dedicated to the design and implementation of advanced engineering technologies that facilitate data acquisition relating to clinical performance.
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Elisabetta Viani Puglisi
Associate Professor (Research) of Structural Biology
Current Research and Scholarly InterestsViral infections and subsequent host response depend on multiple RNA-protein interaction. My research focuses on the structural and functional characterization of RNA-protein complexes involved in viral infection. Current research aims to understand how the Human Immunodeficiency Virus (HIV) initiates its replication upon host infection. We use NMR spectroscopy and x-ray crystallography to study the structure of the initiation complex, formed by a host tRNA and HIV genomic RNA, coupled with biochemical and biophysical methods to understand functional properties. The goal of this research is to gain a molecular view of HIV replication initiation, and use this information to develop new therapeutic approaches to combat HIV.
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Joseph (Jody) Puglisi
Jauch Professor and Professor of Structural Biology
Current Research and Scholarly InterestsThe Puglisi group investigates the role of RNA in cellular processes and disease. We investigate dynamics using single-molecule approaches. Our goal is a unified picture of structure, dynamics and function. We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections. A long-term goal is to target processes involving RNA with novel therapeutic strategies.
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Stephanie Pun, MD
Clinical Associate Professor, Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Pun specializes in the treatment of complex hip disorders with surgical hip preservation options for children, adolescents, and adults. Her goal is to enhance hip function in active individuals and to prevent the early development of hip osteoarthritis.
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Krishna Pundi, MD
Clinical Instructor, Medicine - Cardiovascular Medicine
BioKrishna Pundi, MD is a cardiac electrophysiologist and health services and outcomes researcher with a clinical interest in the management of ventricular arrhythmias and atrial fibrillation.
Dr. Pundi leads a multidisciplinary research program to study (1) clinical and arrhythmia-specific factors that predict cardiovascular risk for ventricular arrhythmias, (2) the interplay of frailty and obesity with atrial fibrillation outcomes, and (3) the role of digital health and wearables in arrhythmia care. He has led grant-funded research through the NIH, FDA, and ACC and collaborations with large device and quality databases including AHA’s Get With the Guidelines. He has a special interest in innovation and regulatory science, having organized national Think Tanks of patients, investigators, and FDA to define the scientific and clinical use of wearable monitors. Dr. Pundi holds leadership roles through the American College of Cardiology, Heart Rhythm Society, Cardiovascular Sciences Research Consortium, and HRX - an innovation-focused meeting of clinicians, researcher, and industry.
