School of Medicine
Showing 481-500 of 574 Results
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Tianwei Du
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Du's clinical interests focus on providing evidence-based treatment to individuals with emotion dysregulation, interpersonal difficulties, and/or complex trauma. She is also passionate about addressing diversity factors in clinical work. Dr. Du provides services in the Dialectical Behavior Therapy (DBT) Adult Program, Stanford Mental Health for Asians Research and Treatment (SMHART) Clinic, and the Anxiety and Depression Adult Psychological Treatment (ADAPT) Clinic. Dr. Du is a bilingual clinician speaking English and Mandarin.
Dr. Du's research focuses on exploring the roles of interpersonal processes and personality in psychopathology, and she has published widely on this topic. Dr. Du also participated in a variety of clinical trials to help develop and improve evidence-based interventions for individuals with complex clinical presentations and populations with limited access to mental health care. -
Justin Du Bois
Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Chemical and Systems Biology
BioThe Du Bois lab is heavily invested in exploring voltage-gated ion channel function and physiology and the underlying role of specific channels in human pathologies, particularly nociception, epilepsy, and neurodevelopmental disorders. With expertise in chemical synthesis, we have access to a collection of exceptional natural products—tetrodotoxin, saxitoxin, gonyautoxin, batrachotoxin, veratridine, antillatoxin, to name a few—that act as selective modulators of sodium ion channels (NaVs). In addition, we have developed novel molecules as inhibitors and agonists of specific voltage-gated chloride (ClCs) and calcium (CaVs) channel isoforms. As a lab, we are uniquely positioned to advance high-precision chemical tools to interrogate underlying biochemical mechanisms of electrogenesis. Our work in this arena is guided by a number of questions related to the basic functioning of voltage-gated channels in neuronal cells and glia that include: 1) what is the rate at which channels are being made and degraded and is the rate of channel turnover context dependent (i.e., is protein turnover affected by increased neuronal activity, nerve cell damage, etc.); 2) to what extent is channel expression and cellular distribution affected by external factors (pH, inflammatory modulators, injury); 3) how do post-translational protein modifications influence channel function and how are such modifications altered in response to external factors; 4) how do neighboring glia influence channel expression and ion gating. Answers to these types of questions will provide a deeper understanding of the molecular mechanisms by which neuronal cells and tissue respond to external stimuli, stress, and injury. We benefit from the strong interest of others in our work and multiple collaborators at Stanford and at other institutions.
Ion channel function and physiology. We wish to understand the role of individual subtypes of voltage-gated sodium, chloride, and calcium channels in neuronal signaling and how structural changes (i.e., point mutations, post-translational modifications, partner proteins) alter channel function. Our interests include the design, development, and application of chemogenetic technologies for targeting individual channel subtypes and allosteric modulators of select channel isoforms. Our work aims to inform efforts in translational research, as voltage-gated ion channel dysregulation and malfunction underlie a wide range of human diseases and disorders.
Natural products synthesis. We are interested in developing efficient and flexible synthetic routes to natural products that serve as ‘lead’ compounds for advancing high precision pharmacological tools. Most of the targets we are interested in obtaining are not available in sufficient quantities from natural sources, thus necessitating de novo preparation. To streamline the assembly process of these complex molecules, we are challenged to develop, in parallel, new tactics and chemical methods that facilitate C–C, C–N, and C–O bond formation.
Toxin ‘sponge’ proteins. A longstanding collaboration with the Minor lab at UCSF has focused on understanding how certain organisms that ingest dietary toxins such as saxitoxin, tetrodotoxin, and batrachotoxin survive their poisonous effects. This work has resulted in the elucidation of the structures of novel paralytic shellfish-binding proteins (so-called saxiphilins) and the toxin ‘binding code’. Studies are ongoing to integrate saxiphilins into a diagnostic device for measuring toxin concentrations in shellfish and to advance an engineered toxin-binding protein as a countermeasure for paralytic shellfish poisoning. -
Monica M. Dua, MD
Clinical Professor, Surgery - General Surgery
Current Research and Scholarly InterestsTechnical aspects of minimally invasive pancreatic and liver surgery
Minimally invasive strategies for the management of pancreatic necrosis
Management of severe acute pancreatitis – academic vs community treatment
Multidisciplinary treatment of HCC; institutional barriers to appropriate referral/ care
Endocrine/exocrine insufficiency after pancreatectomy; volumetric assessment
Natural history and management of pancreatic cysts -
Dawn Duane
Clinical Professor, Pediatric Neurology
Clinical Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsI am a general pediatric neurologist. My interest is in clinical diagnosis and treatment of common neurologic diseases in pediatric patients and teaching feature doctors, neurologists and pediatric neurologists about pediatric neurology.
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Catherine Duarte
Assistant Professor of Epidemiology and Population Health
BioDr. Catherine Duarte is an Assistant Professor in the Department of Epidemiology & Population Health at Stanford University’s School of Medicine. She received her PhD in Epidemiology from the University of California, Berkeley School of Public Health and her Master of Science in Social and Behavioral Sciences from the Harvard T.H. Chan School of Public Health. Duarte’s work evaluates upstream drivers of overall risk for, and heterogeneity in, lifecourse health. Specifically, she examines how education and legal system policy and practice exposures in early life may shape population health and health inequity, with an emphasis on cognitive aging and dementia outcomes in midlife and older age. In doing so, her work aims to contribute to systems-level interventions designed to support population health and wellbeing for collective thriving.
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Anne Dubin
Endowed Professor of Pediatric Cardiology
Current Research and Scholarly InterestsArrhythmia management in pediatric heart failure, especially resynchronization therapy in congenital heart disease,Radio frequency catheter ablation of pediatric arrhythmias,
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Anthony DuBose
Clinical Associate Professor, Medicine - Primary Care and Population Health
Current Research and Scholarly InterestsSoft tissue musculoskeletal injuries with focus on repetitive strain injuries
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Alfredo Dubra, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.
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Piotr Dubrowski
Clinical Instructor, Radiation Oncology - Radiation Physics
BioPiotr Dubrowski is a Canadian trained and board-certified Therapy Medical Physicist. Throughout his career Piotr has had the opportunity to bring several new Cancer Clinics operational from the ground up, where he was able to hone a broad, systems-approach to Radiation Oncology. He was recently promoted to Associate Quality Director of Physics responsible for improving patient safety and workflow/technology improvements across a wide cancer care network. Piotr’s research interests focus mainly on improving the treatment planning process and increasing clinic safety through software development and hardware 3D-print prototyping. Additionally, Piotr has sought out opportunities to give back to the Global community with participation in the Stanford Global Radiation Oncology Outreach efforts expanding education and access to care in Tanzania and Kenya and throughout the developing world via online Radiation Therapy courses.
