Maternal & Child Health Research Institute (MCHRI)
Showing 281-300 of 1,007 Results
-
Jennifer Frankovich
Clinical Professor, Pediatrics - Rheumatology
Current Research and Scholarly InterestsMy primary interest and role at Stanford is to evaluate and treat children with both systemic and organ specific autoimmune disease. In October of 2012, we started a multidisciplinary clinic dedicated to treating patients with PANS (Pediatric Acute-onset Neuropsychiatric Syndromes). I am currently the clinical and research director for the PANS program.
-
Hunter Fraser
Professor of Biology
Current Research and Scholarly InterestsWe study the evolution of complex traits by developing new experimental and computational methods.
Our work brings together quantitative genetics, genomics, epigenetics, and evolutionary biology to achieve a deeper understanding of how genetic variation shapes the phenotypic diversity of life. Our main focus is on the evolution of gene expression, which is the primary fuel for natural selection. Our long-term goal is to be able to introduce complex traits into new species via genome editing. -
Michael Fredericson, MD
Professor of Orthopaedic Surgery and, by courtesy, of Medicine (Stanford Prevention Research Center)
Current Research and Scholarly InterestsMy research focuses on the etiology, prevention, and treatment of overuse sports injuries in athletes and lifestyle medicine practices for improved health and longevity.
-
Richard Frock
Assistant Professor of Radiation Oncology (Radiation and Cancer Biology)
Current Research and Scholarly InterestsWe are a functional genomics laboratory interested in elucidating mechanisms of DNA repair pathway choice and genome instability. We use genome-wide repair fate maps of targeted DNA double strand breaks (DSBs) to develop pathway-specific models and combinatorial therapies. Our expertise overlaps many different fields including: genome editing, ionizing radiation, cancer therapeutics, V(D)J and IgH class switch recombination, repair during transcription and replication, and meiosis.
-
Adam Frymoyer
Clinical Professor, Pediatrics - Neonatology
Current Research and Scholarly InterestsMy research interests focus on understanding the clinical pharmacokinetics (PK) and pharmacodynamics (PD) of medicines used in complex pediatric populations. This includes identifying sources of variation in drug response through the application of population PK-PD modeling and simulation approaches. The goal is to ultimately apply this quantitative understanding to guide therapeutic decision-making in infants and children.
-
Janene Fuerch
Clinical Professor, Pediatrics - Neonatology
BioJanene H. Fuerch, MD is a Clinical Professor of Neonatology at Stanford University Medical Center, as well as an innovator, educator, researcher and physician entrepreneur. She has an undergraduate degree in Neuroscience from Brown University and a medical degree from the Jacobs School of Medicine at SUNY Buffalo. At Stanford University she completed a pediatrics residency, neonatal-perinatal medicine fellowship and the Byers Center for Biodesign Innovation Fellowship.
She is also Assistant Director of the Biodesign Innovation Fellowship Program at Stanford University, and Co-Director of Impact1 where she mentors and advises new entrepreneurs through all aspects of medical device development, from identifying clinical needs to commercialization. Her specific areas of investigational interest include the development and commercialization process of neonatal, pediatric and maternal health medical devices as well as the utilization of a simulated environment to develop and test medical devices. She is a national leader in neonatal resuscitation, ECMO, device development and has been an AHRQ and FDA funded investigator. But her work extends outside of the academic realm to industry having co-founded EMME (acquired by Simple Health 2022) an award-winning reproductive health company, medical director for Novonate (acquired by Laborie 2023) a neonatal umbilical catheter securement company and notable consultant for Vitara (EXTEND - artificial environment to decrease complications of prematurity), and Avanos™. Janene is passionate about improving the health of children and newborns through medical device innovation and research. -
Gerald Fuller
Fletcher Jones Professor in the School of Engineering
BioThe processing of complex liquids (polymers, suspensions, emulsions, biological fluids) alters their microstructure through orientation and deformation of their constitutive elements. In the case of polymeric liquids, it is of interest to obtain in situ measurements of segmental orientation and optical methods have proven to be an excellent means of acquiring this information. Research in our laboratory has resulted in a number of techniques in optical rheometry such as high-speed polarimetry (birefringence and dichroism) and various microscopy methods (fluorescence, phase contrast, and atomic force microscopy).
The microstructure of polymeric and other complex materials also cause them to have interesting physical properties and respond to different flow conditions in unusual manners. In our laboratory, we are equipped with instruments that are able to characterize these materials such as shear rheometer, capillary break up extensional rheometer, and 2D extensional rheometer. Then, the response of these materials to different flow conditions can be visualized and analyzed in detail using high speed imaging devices at up to 2,000 frames per second.
There are numerous processes encountered in nature and industry where the deformation of fluid-fluid interfaces is of central importance. Examples from nature include deformation of the red blood cell in small capillaries, cell division and structure and composition of the tear film. Industrial applications include the processing of emulsions and foams, and the atomization of droplets in ink-jet printing. In our laboratory, fundamental research is in progress to understand the orientation and deformation of monolayers at the molecular level. These experiments employ state of the art optical methods such as polarization modulated dichroism, fluorescence microscopy, and Brewster angle microscopy to obtain in situ measurements of polymer films and small molecule amphiphile monolayers subject to flow. Langmuir troughs are used as the experimental platform so that the thermodynamic state of the monolayers can be systematically controlled. For the first time, well characterized, homogeneous surface flows have been developed, and real time measurements of molecular and microdomain orientation have been obtained. These microstructural experiments are complemented by measurements of the macroscopic, mechanical properties of the films. -
Margaret T. Fuller
Reed-Hodgson Professor of Human Biology, Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Current Research and Scholarly InterestsRegulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.
-
Lawrence Fung MD PhD
Associate Professor of Psychiatry and Behavioral Sciences (Major Laboratories & Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsDr. Lawrence Fung is a physician-scientist specializing in autism and neurodiversity. Dr. Fung is an associate professor of Psychiatry at Stanford University. He is the director of the Stanford Neurodiversity Project (SNP), director of the Neurodiversity Clinic, and PI at the Fung Lab. Dr. Fung’s research traverses from multi-modal neuroimaging studies to a new conceptualization of neurodiversity and its application to clinical, educational, and employment settings. His lab has two main arms of research: (1) neurobiology of autism and (2) neurodiversity.
The neurobiology arm of his lab focuses on advancing the understanding of the thalamocortical circuits and their socio-communicative and cognitive functions in people on the spectrum by using novel neuroimaging and bioanalytical technologies. The findings of his neurobiology research efforts were published in top journals in our field, such as Molecular Psychiatry, Translational Psychiatry, and Psychoneuroendocrinology.
Using a community-based participatory research approach, Dr. Fung’s team devises and implements novel interventions to improve the lives of neurodiverse individuals by maximizing their potential and productivity. He has developed and assessed several psychoeducational interventions, including the Developing Inclusive and Vocational Educational Resources for Success and Employment (DIVERSE) curriculum.
Dr. Fung is also the founding director of the SNP, a special initiative of the Department of Psychiatry at Stanford. Since 2017, the SNP has organized various events, including the Stanford Neurodiversity Summit, which brings thousands of people together yearly to share visions, innovations, and inspirations about maximizing the potential of neurodiversity. Each summer, about 100 high-school students join us at the SNP’s Research, Education, and Advocacy Camp for High Schoolers (SNP-REACH), to learn how to develop neurodiversity advocacy projects. Dr. Fung also teaches a neurodiversity design thinking course at Stanford. Clinically, Dr. Fung has applied the SBMN to his clinical work and is teaching a CME course focusing on delivering neurodiversity-affirmative care to neurodivergent patients. -
Stephen J. Galli, MD
Mary Hewitt Loveless, MD, Professor in the School of Medicine and Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly InterestsThe goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease. We study both the roles of mast cells, basophils, and IgE in normal physiology and host defense, e.g., in responses to parasites and in enhancing resistance to venoms, and also their roles in pathology, e.g., anaphylaxis, food allergy, and asthma, both in mice and humans.
-
Hayley Gans
Current Research and Scholarly InterestsThe focus of my laboratory is the immune response to viral vaccines evaluating the ontogeny of responses in infants and limitations in immunocompromised hosts. We have studied responses to an early two-dose measles immunization, one versus 2 doses of varicella immunization, and polio vaccine in preterm versus term infants. Other active areas of research include measles and varicella immunity in HIV infected individuals, and transplant recipients.
-
Christopher Gardner
Rehnborg Farquhar Professor
Current Research and Scholarly InterestsThe role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines
-
Joseph Garner
Professor of Comparative Medicine and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsThe medical research community has long recognized that "good well-being is good science". The lab uses an integrated interdisciplinary approach to explore this interface, while providing tangible deliverables for the well-being of human patients and research animals.
-
Matthias Garten
Assistant Professor of Microbiology and Immunology and of Bioengineering
Current Research and Scholarly InterestsWith a creative, collaborative, biophysical mindset, we aim to understand the ability non-model organisms to interface with environment to a point at which we can exploit the mechanisms finding cures against diseases and use the mechanisms as tools that we can use to engineer the environment. By developing approaches that allow a quantitative understanding and manipulation of molecular transport our research makes non-model organisms accessible to researchers and engineers.
Specifically, we are studying how the malaria parasite takes control over red blood cells. By learning the biophysical principles of transport in between the host and the parasite we can design ways to kill the parasite or exploit it to reengineer red blood cells. The transport we study is broadly encompassing everything from ions to lipids and proteins. We use variations of quantitative microscopy and electrophysiology to gain insight into the unique strategies the parasite evolved to survive. -
Sergios Gatidis
Associate Professor of Radiology (Pediatric Radiology)
BioDr. Gatidis completed his medical training at the University of Tuebingen / Germany and received his Diploma in Mathematics from from the Universities of Tuebingen and Hagen / Germany. His research is focused on on methods and applications of machine learning for medical data analysis and translation of AI into clinical practice.
-
Brice Gaudilliere
Professor of Anesthesiology, Perioperative and Pain Medicine (MSD) and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly InterestsThe advent of high dimensional flow cytometry has revolutionized our ability to study and visualize the human immune system. Our group combines high parameter mass cytometry (a.k.a Cytometry by Time of Flight Mass Spectrometry, CyTOF), with advanced bio-computational methods to study how the human immune system responds and adapts to acute physiological perturbations. The laboratory currently focuses on two clinical scenarios: surgical trauma and pregnancy.
-
Charles Gawad
Associate Professor of Pediatrics (Hematology/Oncology)
BioOur lab works at the interface of biotechnology, computational biology, cellular biology, and clinical medicine to develop and apply new tools for characterizing genetic variation across single cells within a tissue with unparalleled sensitivity and accuracy. We are focused on applying these technologies to study cancer clonal evolution while patients are undergoing treatment with the aim of identifying cancer clonotypes that are associated with resistance to specific drugs so as to better understand and predict treatment response. We are also applying these methods to understand how more virulent pathogens emerge from a population of bacteria or viruses with an emphasis on developing a deeper understanding of how antibiotic resistance develops.
-
Pascal Geldsetzer
Assistant Professor of Medicine (Primary Care and Population Health) and, by courtesy, of Epidemiology and Population Health
BioPascal Geldsetzer is an Assistant Professor of Medicine in the Division of Primary Care and Population Health and, by courtesy, in the Department of Epidemiology and Population Health. He is also affiliated with the Phil & Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Department of Biomedical Data Science, Department of Health Policy, and the Stanford Center for Population Health Sciences.
His research focuses on identifying and evaluating the most effective interventions for improving health at older ages. In addition to leading several randomized trials, his methodological emphasis lies in the use of natural experiments to ascertain causal effects in large observational datasets, particularly in electronic health record data. He has won an NIH New Innovator Award (in 2022), a Chan Zuckerberg Biohub investigatorship (in 2022), and three NIH R01 grants as Principal Investigator (in 2023 and 2024). In 2026, he was named one of the 100 most influential people in health and medicine globally by TIME Magazine.
