Maternal & Child Health Research Institute (MCHRI)
Showing 41-50 of 1,007 Results
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Ann M. Arvin
Lucile Salter Packard Professor of Pediatrics and Professor of Microbiology and Immunology, Emerita
Current Research and Scholarly InterestsOur laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.
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Euan A. Ashley
Roger and Joelle Burnell Professor of Genomics and Precision Health, Arthur L. Bloomfield Professor of Medicine and Professor of Genetics, of Biomedical Data Science and, by courtesy, of Pathology
Current Research and Scholarly InterestsThe Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.
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Ritu Asija
Clinical Professor, Pediatrics - Cardiology
BioI am a pediatric cardiac intensivist specializing in the care of infants, children, and adults with congenital heart disease and heart failure. As Associate Director of the Pulmonary Artery Reconstruction Program at Stanford, I coordinate multidisciplinary care for patients with complex pulmonary artery abnormalities and right ventricular dysfunction. My clinical and academic interests include innovation in pediatric cardiovascular care, physician well-being, and faculty development. Following my appointment as a Faculty Fellow at the Stanford Center for Biodesign (2019–2020), I have continued to develop novel technologies addressing unmet needs in pediatric medicine. I also serve as a Physician Resource Network supporter, providing peer support to the Stanford School of Medicine community, and have completed the Stanford WellMD Wellness Director course. In addition, I am pursuing coaching certification to further advance faculty development and mentorship. My institutional and national leadership roles include serving on the Stanford School of Medicine Appointments and Promotions Committee and as a member of the American Board of Pediatrics Cardiology Subboard.
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Themistocles (Tim) Assimes
Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsGenetic Epidemiology, Genetic Determinants of Complex Traits related to Cardiovasular Medicine, Coronary Artery Disease related pathway analyses and integrative genomics, Mendelian randomization studies, risk prediction for major adverse cardiovascular events, cardiovascular medicine related pharmacogenomics, ethnic differences in the determinants of Insulin Mediated Glucose Uptake, pharmacoepidemiology of cardiovascular drugs & outcomes
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Laura Attardi
Catharine and Howard Avery Professor of the School of Medicine and Professor of Genetics
Current Research and Scholarly InterestsOur research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.
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Jeffrey Axelrod
Professor of Pathology
Current Research and Scholarly InterestsGenetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization.
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Muriel Babey
Assistant Professor of Medicine (Endocrinology)
BioMuriel Babey, M.D. is an Assistant Professor of Medicine in the Division of Endocrinology, Gerontology & Metabolism at Stanford University. She is a physician–scientist who specializes in metabolic bone disease and osteoporosis, with a focus on skeletal health during reproductive transitions and aging, as well as disorders of calcium and parathyroid metabolism.
Originally from Switzerland, Dr. Babey earned her medical degree in Switzerland and completed fellowship training in Endocrinology at the University of California, San Francisco. During her postdoctoral training in the laboratory of Holly Ingraham at UCSF, her work focused on identifying CCN3 as a maternal brain–derived osteoanabolic hormone critical for lactation, uncovering a previously unrecognized neuroendocrine axis regulating bone formation and marrow adiposity.
Dr. Babey directs a research program that integrates human cohort studies with mechanistic models to define endocrine pathways coordinating skeletal and metabolic resilience across reproductive transitions and aging. Her work centers on identifying secreted factors and interorgan communication networks that regulate bone health, with the goal of advancing translational strategies for osteoporosis and related metabolic diseases. Her research is supported by an NIH K08 award, and she is a recipient of the Endocrine Society Early Investigator Award and the ASBMR John Haddad Early Investigator Award. -
Rosa Bacchetta
Professor (Research) of Pediatrics (Stem Cell Transplantation)
Current Research and Scholarly InterestsIn the coming years, I plan to further determine the genetic and immunological basis of diseases with autoimmunity or immune dysregulation in children. I believe that much can still be learned from the in depth mechanistic studies of pediatric autoimmune diseases. Genomic analysis of the patients' samples has become possible which may provide a rapid indication of altered target molecules. I plan to implement robust functional studies to define the consequences of these genetic abnormalities and bridge them to the patient's clinical phenotype.
Understanding functional consequences of gene mutations in single case/family first and then validating the molecular and cellular defects in other patients with similar phenotypes, will anticipate and complement cellular and gene therapy strategies.
For further information please visit the Bacchetta Lab website:
http://med.stanford.edu/bacchettalab.html -
Laura K. Bachrach
Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital, Emerita
Current Research and Scholarly InterestsPrevention of osteoporosis begins in childhood and adolescence by measures that maximize acquistion of bone mineral during the critical adolescent years. Body mass, calcium nutriture, physical activity, growth and sex steroid hormones, and genetic factors are all thought to be important determinants of bone mass although the relative contribution of each remains controversial.
