Maternal & Child Health Research Institute (MCHRI)
Showing 181-190 of 211 Results
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Annika M. Weber
Postdoctoral Scholar, Gastroenterology
BioAnnika is a postdoctoral scholar in the Spencer Lab studying how gut microbes metabolize prebiotic fibers to produce bioactive metabolites linked to lowering disease risk. She holds an MS in Human Nutrition from the University of Sheffield and a PhD in Food Science and Human Nutrition from Colorado State University. Her work integrates multi-omic approaches to map diet-microbe-metabolite relationships. Annika aims to translate these mechanistic insights into microbiome-informed dietary strategies for reducing chronic diseases.
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Alexis Thomas Weiner
Postdoctoral Scholar, Pathology
Current Research and Scholarly InterestsThe planar cell polarity (PCP) signaling pathway polarizes animal cells along an axis parallel to the tissue plane, and in so doing generates long-range organization that can span entire tissues. Although its core proteins and much about their interactions are known, how PCP signaling occurs at a mechanistic level remains fundamentally mysterious. In my current project I will employ novel genetic methods to dissect the logic underlying how cellular asymmetry arises at a molecular level.
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Yuyin Xiao
Postdoctoral Scholar, Economics
BioYuyin Xiao is the postdoctoral researcher of the Freeman Spogli Institute for International Studies at Stanford University. She received her MS and PhD from Shanghai Jiaotong University. Her research focuses almost exclusively on low- and middle-income countries and is concerned with: health policy, including health equity, supply, demand and utilization of health service programs, and research on health service systems; health technology and innovation, including digital health, development of digital health tools, and evaluation of the effectiveness of digital interventions. Yuyin’s papers have been published in leading academic journals, including British Medical Journal, Journal of Medical Internet Research, Journal of Biomedical Informatics, BMC Public Health and others.
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熊剑 (Jian Xiong)
Postdoctoral Scholar, Chemical Engineering
BioI thrive to understand the roles of lysosomes in physiological and pathological conditions. Lysosomes are both degradation compartment and metabolic controlling hub, and dysregulation of lysosomal functions are frequently implicated in a vast number of diseases including neurodegenerative diseases, however, the systematic knowledge of the molecular mechanism by which lysosomal contributes to these diseases is lacking. Ion channels are the primary mediators of neuronal activity, defects in neuronal ion channel activity are linked with many kinds of neurodegenerative diseases. Interestingly, besides typical ion channels that are involved in the neuronal activity, defects in lysosomal ion channels, such as TRPML1, CLN7 and CLC-7 are also implicated in neuropathy. My previous work as Ph.D student in University of Texas MD Anderson Cancer Center focused on regulation of lysosomal function by ion channels and metabolites. I discovered a mechanism of lysosomal Na+ channel regulate mTORC1 activation by regulating lysosomal amino acid accumulation. I also discovered role of glutamine in controlling lysosomal degradation capacity. In the meantime, I developed novel methods to isolate organelles. My ultimate research goal is to understand the key developmental pathways and how alterations in gene sequences and expression contribute to human disease, therefore, I am pursuing independent academic researcher as my career goal. Starting Feb 2022, I work with Dr. Monther Abu-Remaileh at Stanford University on role of lysosomes in neurodegenerative diseases. I use genetics, chemical biology and omics approaches to study lysosome function under various physiological and pathological conditions, especially age-associated neurodegenerative disorders, and monogenic neurodegenerative lysosome storage diseases. In Stanford, I aim to integrate ionic regulation, metabolomic regulation and functional proteomic regulation to systematically understand the biology of lysosome in physiological conditions and pathological conditions.
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Liu Yang
Postdoctoral Scholar, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsMy current focus lies in analyzing bedside monitoring waveforms and electronic health record data to understand their correlations with adverse conditions in premature infants, and to explore effective solutions that can enhance the outcomes for these vulnerable patients.
