Maternal & Child Health Research Institute (MCHRI)
Showing 21-40 of 69 Results
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Kevin Kelley
Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)
BioAs a neuroscientist and psychiatrist, I am motivated by how little we understand about the pathophysiology of psychiatric disorders and hope that further knowledge will help to alleviate the ongoing distress of many of our patients. My research program leverages computational genomics, human brain cellular models, and molecular neuroscience techniques to understand the cellular and molecular mechanisms of human brain development and how dysfunction in these processes lead to psychiatric disorders.
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John Kerner
Professor of Pediatrics (Gastroenterology), Emeritus
Current Research and Scholarly InterestsI am interested in pediatric nutritional support and have experience evaluating new enteral and parenteral products especially for the neonate (I studied a "new" I.V. fat product for Abbott; I participated in a multicenter trial of a formula with fish oil in it for neonates with Mead Johnson and a multicenter trial of a new human milk fortifier for Wyeth).
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Michelle Joanne Khan, MD, MPH, FACOG (she/her)
Clinical Professor, Obstetrics & Gynecology - General
Current Research and Scholarly InterestsDr. Khan's research focuses on prevention of HPV-related cancers of the cervix, vagina, vulva, and anus and on the impact of reproductive tract infections on pregnancy and health.
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Kajal Khanna
Clinical Associate Professor, Emergency Medicine
Clinical Associate Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsGlobal pediatric emergency medicine research, educational scholarship, pediatric emergency medical care in low- and middle- income countries and rights-based approaches to health systems development
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Nasim Sabery Khavari
Clinical Associate Professor, Pediatrics - Gastroenterology
Current Research and Scholarly InterestsPediatric Gastroenterology, Celiac Disease, Nutrition in Celiac Disease
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Paul A. Khavari, MD, PhD
Carl J. Herzog Professor of Dermatology in the School of Medicine
Current Research and Scholarly InterestsWe work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.
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Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine. -
Peter S. Kim
Virginia and D. K. Ludwig Professor of Biochemistry
Current Research and Scholarly InterestsOur research focuses on developing new strategies for vaccine creation. We also aim to generate vaccines targeting infectious agents that have eluded efforts to date. We integrate experimental approaches with protein language models to guide artificial evolution and enable efficient antibody and protein engineering. Our interdisciplinary approach aims to address critical global health challenges.
