School of Medicine
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Paul George, MD, PhD
Associate Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsCONDUCTIVE POLYMER SCAFFOLDS FOR STEM CELL-ENHANCED STROKE RECOVERY:
We focus on developing conductive polymers for stem cell applications. We have created a microfabricated, polymeric system that can continuously interact with its biological environment. This interactive polymer platform allows modifications of the recovery environment to determine essential repair mechanisms. Recent work studies the effect of electrical stimulation on neural stem cells seeded on the conductive scaffold and the pathways by which it enhances stroke recovery Further understanding the combined effect of electrical stimulation and stem cells in augmenting neural repair for clinical translational is a major focus of this research going forward.
BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for stroke and neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration and stroke recovery. Recent work utilizing these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.
APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes. -
Pejman Ghanouni, MD, PhD
Associate Professor of Radiology (Body MRI) and, by courtesy, of Neurosurgery, of Obstetrics and Gynecology and of Urology
BioDr. Ghanouni is a board-certified, fellowship-trained diagnostic radiologist with Stanford Health Care Radiology. He is an associate professor in the Department of Radiology, Division of Body MRI at Stanford University School of Medicine, and by courtesy, of Urology, of Neurosurgery, and of Obstetrics and Gynecology.
Dr. Ghanouni is the director of the Stanford Health Care Minimally Invasive MR Interventional Center (MIMRIC) and the Focused Ultrasound Center of Excellence. He is also chief of the Division of Body MRI at Stanford University School of Medicine.
Dr. Ghanouni is recognized around the world for his extensive expertise in using advanced imaging to diagnose, manage, and treat a wide range of conditions and disorders. As a renowned leader in diagnostic and MRI-guided interventional radiology, Dr. Ghanouni creates a customized care plan for each of his patients.
Dr. Ghanouni’s research interests include the latest advances in MR-guided focused ultrasound techniques to treat essential tremor, Parkinson’s disease, prostate cancer, bone tumors, desmoid tumors, and uterine fibroids. An experienced physician-scientist, Dr. Ghanouni has collaboratively led clinical trials and research initiatives that explore treatments for epilepsy, pancreatic cancer, and several types of tumors. Through these clinical trials, Dr. Ghanouni has helped secure FDA approval for many MR-guided focused ultrasound treatments.
His articles have been published in dozens of peer-reviewed medical journals, including Lancet Oncology, Neurology, Investigative Radiology, European Radiology, Journal of Magnetic Resonance Imaging, Journal of Neurosurgery, New England Journal of Medicine, and Radiology. Dr. Ghanouni has been invited to speak at conferences and symposiums all over the nation and the world, including in Rome, Italy; Tel Aviv, Israel; and Riyadh, Saudi Arabia. He is widely regarded for his groundbreaking research as well as his clinical expertise.
Dr. Ghanouni is a member of several professional organizations, including the International Society for Magnetic Resonance in Medicine, the International Society for Therapeutic Ultrasound, and the European Focused Ultrasound Society.
MR-guided focused ultrasound treatment: https://www.youtube.com/watch?v=3Bwq2YxD9eU -
Iris C. Gibbs, MD, FACR, FASTRO
Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery
On Leave from 05/01/2024 To 04/22/2025Current Research and Scholarly InterestsDr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.
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Carl Gold
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Associate Professor (By courtesy), NeurosurgeryBioDr. Gold is a board-certified neurologist who is fellowship-trained in the diagnosis and treatment of neurological disorders in hospitalized patients. He cares for a broad range of patients, including individuals with seizures, central nervous system infections, autoimmune diseases, headaches, neuromuscular conditions, and neurological complications of cancer.
Dr. Gold serves as Vice Chair of Quality, Safety, & Experience for the Department of Neurology & Neurological Sciences. In this role, he coordinates projects aimed at improving care for patients with neurological conditions across the health system. He also serves as Medical Director of Service Excellence for Stanford Health Care.
For more information on the Stanford Neurohospitalist Program & Fellowship, please visit: https://med.stanford.edu/neurology/divisions/neurohospitalist.html
Learn more about the Stanford Neurology Communication Coaching Program by visiting: http://med.stanford.edu/neurology/education/resident-coaching.html
Additional information on Stanford Neurology's efforts in Quality, Safety, & Value can be found here: http://med.stanford.edu/neurology/quality.html
