School of Medicine
Showing 1-5 of 5 Results
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Palca Shibale
Postdoctoral Scholar, Plastic and Reconstructive Surgery
BioShibale, Palca is a post-doctoral fellow in the Hagey Laboratory under mentorship of Dr. Derrick Wan and Michael Longaker. She earned her BS in Molecular and Cellular Biology at the University of Washington (UW), her MS in Medical Physiology and Biophysics at Case Western University and her MD from UW. She has previously conducted translational research on drug efficacy and clinical research in trauma and vascular surgery. Her current works focus on understanding the mechanisms of tissue regeneration and fibrosis with nano materials and as well, the roles of fibroblast subpopulations in the foreign body response model
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Antonio Tomasso
Postdoctoral Scholar, Plastic and Reconstructive Surgery
BioAntonio Tomasso is an NWO Rubicon Postdoctoral Scholar. As part of his MSc in Medical Molecular and Cellular Biotechnology at Vita-Salute San Raffaele University, he explored the immunomodulatory and neurotrophic roles of neural stem cells (NSCs) following spinal cord injury. As a Research Assistant at Karolinska Institute, he delved into the signaling pathways required for NSC activation and migration after spinal cord injury, and the limited regenerative abilities of mouse and human heart.
During his PhD, he investigated the molecular mechanisms of tissue regeneration in planarians, axolotls and spiny mice. He conducted research as a Visiting Fellow at the University of Kentucky and the Hubrecht Institute.
His research demonstrated that MAPK/ERK signaling acts as a molecular switch between regeneration and fibrosis in adult mammals and can be activated to stimulate a regenerative response, including new hair follicle formation, in scarring wounds.
He contributed to a pioneering study showing that spiny mice can recover heart function after infarct through enhanced angiogenesis, ECM remodeling and epicardium regeneration. He also played a key role in spatial transcriptomic studies that defined regenerative and fibrotic gene signatures in spiny mice, laboratory mice and gerbils.
He earned a PhD cum laude in Molecular and Cellular Life Sciences at the Max Planck Institute for Molecular Biomedicine.
He has been awarded an NWO Dutch Research Council Rubicon Postdoctoral grant to conduct research on the molecular drivers of fibroblast activation in wound healing and organ fibrosis.
His ultimate research aim is to crack the code of tissue regeneration and rejuvenation, reversing organ scarring and preventing fibrosis in injuries and pathological conditions, through the identification of therapeutic targets for enhanced tissue repair and functional recovery.
Driven by his innate curiosity and passion for science, he loves tackling new challenges, thinking outside the box, and building interdisciplinary collaborations to push forward the boundaries of knowledge.
His career goal is to serve as a group leader, fostering a collaborative environment where everyone can thrive, achieve their goals and leave a lasting impact through community-building and scientific discoveries for the benefit of humankind.
