School of Medicine
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Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsOur lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.
Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsOne of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
Jennifer L. Bruno
Senior Research Scholar, Psychiatry and Behavioral Sciences - Interdisciplinary Brain Sciences
Current Research and Scholarly InterestsDr Bruno is a translational researcher at the interface of developmental cognitive neuropsychology and neurobiology. Her research aims to understand the basis of typical and atypical brain development. An overarching goal of her work is to understand when, how and why individuals with neurodevelopmental and neuropsychiatric disorders fall off the trajectory of typical brain development.
Douglas L. Brutlag
Professor of Biochemistry, Emeritus
Current Research and Scholarly InterestsMy primary interest is to understand the flow of information from the genome to the phenotype of an organism. This interest includes predicting the structure and function of genes and proteins from their primary sequence, predicting function from structure simulating protein folding and ligand docking, and predicitng disease from genome variations. These goals are the same as the goals of molecular biology, however, we use primarily computational approaches.
Matias Bruzoni, MD FACS
Associate Professor of Surgery (Pediatric Surgery)
Current Research and Scholarly InterestsMinimal Access Surgery
Sutured vs Sutureless Gastroschisis Closure
Ultrasound vs anatomic landmark central line placement
Hispanic Center for Pediatric Surgery