School of Medicine
Showing 81-90 of 109 Results
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Shoa L. Clarke, MD, PhD
Assistant Professor of Medicine (Cardiovascular Medicine) and of Pediatrics
BioDr. Clarke is a preventive cardiologist and a physician-scientist focused on disease prevention. He earned his undergraduate degree in human biology from the Division of Nutritional Sciences at Cornell University before obtaining his MD and PhD (genetics) from Stanford University School of Medicine. He has completed clinical training in internal medicine (Brigham & Women’s Hospital), pediatrics (Boston Children’s Hospital), and cardiovascular medicine (Stanford Hospital), and he is board certified in all three specialties. His research is focused on 1) understanding complex disease genetics in diverse populations, 2) integrating monogenic and polygenic risk with clinical risk, 3) large-scale phenotyping using the electronic health record and medical images. His clinical practice focuses on identifying risk factors for cardiovascular disease with the goal of promoting health and longevity through evidence-based personalized treatment. He is interested in developing family-centric approaches for the treatment of adults and children carrying genetic risk for disease.
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Carol Clayberger
Professor (Research) of Pediatrics, Emerita
Current Research and Scholarly InterestsOur group uses molecular biology, biochemistry, and cellular immunology to investigate the activation and effector function of T lymphocytes. Research in the laboratory is currently focused on three areas: granulysin, a lytic molecule expressed late (7-12 days) after T cell activation; identification of correlates of immunity in diseases such as tuberculosis; and tolerance. The long term goal of this work is to develop new ways to treat human disease.
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Harvey Cohen
Deborah E. Addicott - John A. Kriewall and Elizabeth A. Haehl Family Professor of Pediatrics, Emeritus
Current Research and Scholarly InterestsMy research interests extend from hypothesis-driven studies in biochemistry and cell biology to discovery-driven interests in proteomics and systems biology to clinical treatment of acute lymphoblastic leukemia of children, and pediatric palliative care.
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Pasqualina Colella
Sr Res Scientist-Basic Life, Pediatrics - Genetics
BioDr. Pasqualina Colella is a scientist with extensive expertise in cell therapy and gene therapy approaches for the treatment of inherited diseases. She is currently Research Scientist at Stanford University, where she is developing innovative cell therapy approaches to address neuropathic lysosomal storage diseases (LSDs) using hematopoietic stem cell transplantation (HSCT) and genome editing.
Dr. Colella received her summa cum laude Bachelor of Science degree in Biology from the University of Naples Federico II (Italy) and her PhD in Human Genetics from The Open University (UK) at the Telethon Institute of Genetics and Medicine (TIGEM, Italy). During her PhD, she focused on investigating AAV gene therapy for inherited blindness and developed novel strategies to effectively express large (> 5 kb) genes in the retina for treating Stargardt disease and Usher Syndrome type I B, both of which cause untreatable forms of blindness.
After the PhD, Dr. Colella secured prestigious Postdoctoral fellowships from the Marie Skłodowska-Curie Actions (EU) and Genethon (France). As Postdoc she developed innovative in vivo AAV gene therapy approaches based on liver gene transfer or multi-tissue gene expression to target the multi-organ manifestations of Pompe disease, a LSD that presents with neuromuscular impairment.
Dr. Colella is committed to researching innovative ways to combat genetic diseases and making a positive impact on the lives of patients. -
Ruben J Colman, MD, PhD
Instructor, Pediatrics - Gastroenterology
BioDr. Colman is a pediatric gastroenterologist and physician-scientist with an overarching goal to improve and optimize the quality of care and outcomes for children with pediatric inflammatory bowel disease (IBD) through precision medicine approaches. His interdisciplinary team science research program focuses on making precision medicine clinically actionable through innovative solutions merging clinical pharmacology knowledge with ‘-omics’ discoveries using microbiome and metabolomics signatures. Part of this work includes translating these findings into improved clinical treat-to-target endpoints with immediate noninvasive point-of-care measures such as intestinal ultrasound.
The foundation of his current work originates from his PhD titled ‘Precision Dosing and Personalized Medicine in pediatric IBD’. During his training, Dr. Colman was also an American Gastroenterological Association (AGA) editorial fellow for Gastroenterology and he is actively involved in the committees of several professional societies including the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and the Crohn’s and Colitis Foundation. Dr. Colman is currently supported by Early Career Awards of the Thrasher Research Fund, the NASPGHAN Foundation and the Stanford Medicine Children’s Health Center for IBD and Celiac Disease Research Program. -
Carol Conrad
Professor of Pediatrics (Pulmonary Medicine)
On Leave from 08/01/2023 To 06/15/2024Current Research and Scholarly InterestsI am interested in studying the effects of inflammation in the lung, in particular, how N-acetylcysteine may affect and decrease that in CF patients. I am the PI of a multi-center study researching this question. Additionally, in a separate study involving children who have received lung transplants, I am a participating site in an NIH-sponsored observational and mechanistic multi-center study that will examine the role of viral infections in causing chronic graft rejection.
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Christopher H. Contag
Professor of Pediatrics (Neonatology), Emeritus
Current Research and Scholarly InterestsWe develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in "a vacuum" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.
