School of Medicine
Showing 21-40 of 57 Results
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Dr. Qiwen Deng
Postdoctoral Scholar, Pathology
BioHow fibroblasts participate in the organ fibrosis and whether targeting fibroblasts is a good strategy to reverse fibrosis is still a mystery. We have identified two important immune checkpoints, CD47 and PD-L1, are highly expressed in fibroblasts and blocking CD47 and PD-L1 reversed lung fibrosis. This is a prove of concept that targeting immune regulatory pathways could be an effective therapeutic approach to treat fibrotic diseases. In addition to identifying novel targets for the treatment of fibrosis, I am also interested in the crosstalk between fibroblasts and innate immune cells in the development of fibrosis. Combined with cutting-edge NGS approaches including single cell sequencing, spatial transcriptomics and high-dimensional CyTOF technique, we have identified several potential targets and characterized immune cells landscape in lung fibrosis. In the long run, I will focus on the validation of these targets. Specifically, I will apply gain- and loss-function approaches to investigate their role in fibrosis in vitro and in vivo.
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Jimbo Dickerson
Postdoctoral Medical Fellow, Oncology
Masters Student in Health Policy, admitted Autumn 2022
Fellow in Medicine
Resident in MedicineBioI am a medical oncology fellow with a clinical focus on breast cancer, and a research focus on examining cancer care delivery and resource allocation in both high- and low-income contexts. I am currently in my final year of fellowship, working on a Masters in health policy, and doing post-doctoral research on a T32 in the health policy department. My post-doctoral work is divided between domestic policy research, which focuses on analyzing cost and care variation, and global oncology projects, which concentrate on implementation and care delivery.