School of Medicine
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Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsMalaria is a parasitic disease transmitted by mosquitos that is a leading cause of childhood mortality globally. Public health efforts to control malaria have historically been hampered by the rapid development of drug resistance. The goal of our research is to understand the molecular determinants of critical host-pathogen interactions in malaria, with a focus on the erythrocyte host cell. Our long-term goal is to develop novel approaches to prevent or treat malaria and improve child health.
Postdoctoral Scholar, Microbiology and Immunology
BioAsuka Eguchi, PhD is a postdoctoral fellow working with Helen Blau, PhD at Stanford University. Her interests lie in understanding how cells sense and respond to genotoxic stress. Currently, she is developing therapeutic strategies to combat heart failure in Duchenne muscular dystrophy. Dr. Eguchi received her BS in Biology at the University of Alabama in Huntsville. As a graduate student, she developed an Artificial Transcription Factor library to interrogate transcriptional networks that control cell fate decisions under the mentorship of Aseem Ansari, PhD. During her postdoctoral research, she discovered that a telomere binding protein can rescue disease phenotypes of Duchenne muscular dystrophy in cardiomyocytes differentiated from patient-derived induced pluripotent stem cells. Dr. Eguchi is also developing gene therapies that address heart failure in Duchenne and Becker patients. She is a recipient of the Translational Research and Applied Medicine Award and an American Heart Association fellow.
Associate Professor of Medicine (Infectious Diseases) and of Microbiology and ImmunologyOn Leave from 11/22/2021 To 06/19/2022
Current Research and Scholarly InterestsOur basic research program focuses on understanding the roles of virus-host interactions in viral infection and disease pathogenesis via molecular and systems virology single cell approaches. This program is combined with translational efforts to apply this knowledge for the development of broad-spectrum host-centered antiviral approaches to combat emerging viral infections, including dengue, coronaviruses, encephalitic alphaviruses, and Ebola, and means to predict progression to severe disease.