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Postdoctoral Research Fellow, Psychiatry
Current Research and Scholarly InterestsI have been venturing the career of characterizing insulin resistance genes, as the underlying risk factor of type 2 diabetes and metabolic syndrome. My earlier postdoctoral fellowship at the Department of Cardiovascular Medicine involved the functional genomic of diabetes and glycemic traits loci by using deep phenotyping approach i.e., multi-OMICs and transgenic mice.
At my current research, I am harnessing the epigenomic analysis in the global birth cohorts. I aim to unravel the origin of insulin resistance in the etiology of diabetes, mild cognitive impairment, and Alzheimer's diseases. Certain ethnicities develop insulin resistance and diabetes even with the normal weight and at younger ages. Therefore, it is essential to distinguish genes that predispose high-risk individuals to insulin resistance in the presence or absence (lipodystrophy) of obesity.
The main plan of my research is to expand follow-up studies on the global birth cohorts from diverse ethnic groups to eventually enable precise screening. This aim is aligned with the missions of Stanford Long-Range Planning and Precision Health to diminish health disparities. Therefore, our research supports the University mission of deep phenotyping and care of diverse patients and populations. These studies have the potential to specify mechanistic and causality insights from the drivers of diabetes and insulin resistance risk in different ethnicities. The ultimate goal of my research is to pave the way for opportunities to prevent insulin resistance as early as 10-20 years before the onset of diabetes and the age-related adverse outcomes such as vascular dementia and to reduce the widening ethnic inequalities.
My overall goal is to promote the field of global precision medicine with an eye toward the minority and under-represented communities in genomic medicine.
William O Faustman
Clinical Professor (Affiliated) [Vapahcs], Psychiatry and Behavioral Sciences
Staff, Psychiatry and Behavioral Sciences
BioDr. Faustman received his doctorate in clinical psychology from the University of Mississippi and completed his internship at the VA Palo Alto Health Care System. He has an active interest in training, administration, forensic practice, and clinical care in inpatient psychiatry. His research interests have focused on severe mental illness with an emphasis in areas such as cognition and clinical assessment.. He serves as a member of the Stanford IRB and coordinates the American Psychological Association accredited postdoctoral fellowship program at the VA Palo Alto. He holds Chartered Psychologist status with the British Psychological Society,
Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsAutism and Asperger's Disorder.
Genetically-based neurodevelopmental disorder, including Velocardiofacial Syndrome, Smith-Magenis Syndrome, Williams Syndrome, and Fragile X Syndrome.
Intellectual Disability (mental retardation) and psychiatric disorders.
Developmental Language Disorder and Learning Disabilities.
Sensory impairment in children, including visual and hearing impairment.
Psychiatric aspects of medical illness and disability in children.