School of Medicine
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Paul George, MD, PhD
Assistant Professor of Neurology and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsCONDUCTIVE POLYMER SCAFFOLDS FOR STEM CELL-ENHANCED STROKE RECOVERY:
We focus on developing conductive polymers for stem cell applications. We have created a microfabricated, polymeric system that can continuously interact with its biological environment. This interactive polymer platform allows modifications of the recovery environment to determine essential repair mechanisms. Recent work studies the effect of electrical stimulation on neural stem cells seeded on the conductive scaffold and the pathways by which it enhances stroke recovery Further understanding the combined effect of electrical stimulation and stem cells in augmenting neural repair for clinical translational is a major focus of this research going forward.
BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for stroke and neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration and stroke recovery. Recent work utilizing these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.
APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes.
Iris C. Gibbs, MD, FACR, FASTRO
Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsDr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Associate Professor (By courtesy), Neurosurgery
BioDr. Gold is a board-certified neurologist who is fellowship-trained in the diagnosis and treatment of neurological disorders in hospitalized patients. He cares for a broad range of patients, including individuals with seizures, central nervous system infections, autoimmune diseases, headaches, neuromuscular conditions, and neurological complications of cancer. Dr. Gold's primary research interest focuses on enhancing the communication skills of neurology residents, and he serves as the Director of the Stanford Neurology Residency Communication Coaching Program. He is also the Fellowship Director of the Stanford Neurohospitalist Fellowship.
Dr. Gold serves as Vice Chair of Quality, Safety, & Experience for the Department of Neurology & Neurological Sciences. In this role, he coordinates projects aimed at improving care for patients with neurological conditions across the health system.
For more information on the Stanford Neurohospitalist Program & Fellowship, please visit: https://med.stanford.edu/neurology/divisions/neurohospitalist.html
Learn more about the Stanford Neurology Communication Coaching Program by visiting: http://med.stanford.edu/neurology/education/resident-coaching.html
Additional information on Stanford Neurology's efforts in Quality, Safety, & Value can be found here: http://med.stanford.edu/neurology/quality.html
Gerald Grant, MD, FACS
Botha Chan Endowed Professor
Current Research and Scholarly InterestsDr. Grant directs a Blood-brain Barrier Translational Laboratory focusing on enhancing drug delivery to brain tumors in children.