School of Medicine
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Daniel Jarosz
Senior Associate Dean, Basic Science, Professor of Chemical and Systems Biology and of Developmental Biology
Current Research and Scholarly InterestsMy laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.
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Patrick Jurney
Affiliate, Chemical and Systems Biology Operations
Visiting Scholar, Chemical and Systems Biology OperationsBioPatrick Jurney is the Kordestani Endowed Chair and an Associate Professor of Biomedical Engineering at San Jose State University. A Fellow of the American Heart Association (FAHA), his research focuses on the intersection of fluid dynamics and cellular mechanics, with a particular emphasis on cardiovascular health and disease..
Dr. Jurney completed his Ph.D. in Thermal Fluid Systems at the University of Texas at Austin, where he designed and built microphysiological systems to investigate the role of nanoparticle properties in targeted drug delivery. Following his doctoral studies, he was a T-32 Fellow in Translational Engineering at Oregon Health & Science University (OHSU). During his fellowship, he worked with cardiovascular biomaterials and characterized how biomaterial properties influence endothelialization and thrombogenesis.
Currently, his research laboratory at SJSU investigates the role of fluid shear stress mechanotransduction on endothelial metabolic structure and function. Dr. Jurney is a pioneer in using holotomographic microscopy to study sub-cellular organelles in cardiovascular disease. He is also collaborating in the laboratory of Dr. Daria Mochly-Rosen to characterize the role of mitochondrial structure and dynamics in metabolic function in response to ischemia/reperfusion and other models of cardiovascular health and disease.
Website: https://www.jurneylab.org/
Email: patrick.jurney@sjsu.edu or pjurney@stanford.edu
