School of Medicine
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Karthikeshwar Kasirajan (Kasi)
Clinical Professor, Surgery - Vascular Surgery
BioDr. Kasirajan is a board-certified, fellowship-trained vascular surgeon. Also known as Dr. Kasi, he is a clinical professor of vascular surgery at Stanford University School of Medicine.
Dr. Kasirajan preserves limbs, facilitates access to dialysis, and helps his patients manage conditions such as aneurysms, varicose veins, thoracic outlet syndrome, and deep vein thrombosis. Many of his limb preservation patients smoke, have diabetes, or are experiencing renal failure. Dr. Kasirajan’s experience also centers around the treatment of aneurysms and prevention of strokes.
In all cases, his goal is to provide either noninvasive or minimally invasive management whenever possible. He performs open surgery only when it is the best option. Dr. Kasirajan treats many patients with stents and stent grafts, which can shorten hospital stays and recovery times.
Dr. Kasirajan (Kasi) receives referrals of patients from primary care physicians, nephrologists, podiatrists, cardiologists, woundcare specialists, diabetologists, neurologists, and other specialists. He welcomes referrals as early as possible, ideally before patients become symptomatic. A strong proponent of doing early screening for peripheral artery disease, Dr. Kasirajan advocates for the use of the ankle-brachial index (ABI) in routine physical examinations. When providers detect an imbalance between leg and arm blood pressure, Dr. Kasirajan can help create customized strategies to address the cause before the problem worsens.
In addition to offering excellent vascular care to the community, Dr. Kasirajan joined Stanford to continue pursuing his research interests. He has conducted research into advances in minimally invasive procedures for stroke prevention and for aneurysm management. His research has also focused on how to improve surgery outcomes to help patients suffering from peripheral vascular disease. Dr. Kasirajan has been the investigator in over 40 multicenter studies involving new stent graphs, thrombectomy catheters, and other advances in endovascular technology.
Dr. Kasirajan has made more than 100 presentations worldwide on minimally invasive vascular surgery techniques and preventive care in the vascular patient. He has spoken at multiple conferences including the Society for Vascular Surgery, Peripheral Vascular Society, and the South Asian American Vascular Society. He has earned numerous honors for his academic achievements, including the prestigious Alpha Omega Alpha award for medical student and resident education.
As the author of more than 120 journal articles, Dr. Kasirajan’s work has appeared in the Journal of Vascular Surgery, Endovascular Today, Pharmacogenomics Journal, Catheter Cardiovascular Intervention, and many other publications. He also has authored 20 book chapters in textbooks including Medical Management of the Surgical Patient 5th Edition, Advances in Phlebology and Venus Surgery Volume 1, Current Therapy in Vascular Surgery, Mastery of Surgery, and many more.
Dr. Kasirajan has served on the editorial boards of the Journal of Endovascular Therapy, Annals of Vascular Surgery, International Journal of Angiology, and other publications.
Assistant Professor of Surgery (Vascular Surgery)
BioDr. Klarin received bachelor’s degrees in both chemistry and the biological sciences from Cornell University, and his medical degree from the UCLA School of Medicine. He trained in general surgery at the Massachusetts General Hospital and then completed fellowship training in Vascular Surgery at the University of Florida College of Medicine. He is currently appointed as an Assistant Professor in the Department of Surgery at Stanford University School of Medicine within the Division of Vascular Surgery, and also practices at the VA Palo Alto Health Care System (VAPAHCS). His clinical interests include aortic aneurysms, peripheral artery disease (PAD), and mesenteric occlusive disease.
His research uses genomic approaches to better understand the etiology of atherosclerosis, vascular disease, and their associated risk factors including lipids and thrombosis. The foundation of this work is based on two key insights: 1) vascular disease, including Peripheral Artery Disease (PAD), is strongly influenced by inheritance with severe, early-onset disease often clustering in families; 2) differences in DNA sequence variants, both germline and somatic, play a causal role in determining who exhibits such atherosclerotic disease risk. His current use of translational approaches to vascular disease builds on experience and training in genetic analysis of atherosclerosis using bioinformatics and computational-based approaches learned during a post-doctoral fellowship at the Broad Institute of Harvard and MIT.