School of Medicine
Showing 81-90 of 739 Results
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Ming Jeffrey Kao, PhD, MD
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests1. Patient-reported outcomes. Efficient, multi-feature item-response theory (IRT) based computerized adaptive testing (CAT) algorithm using item banks from PROMIS and NIH Toolbox
2. Activity monitoring. Novel analytic framework for physical activity monitoring in the context of pain.
3. Operations research. Multi-variable discrete and continuous optimization for Lean Hospital Management
4. National trends in pain medication prescription -
Peter Kao
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsOur research program has several active projects:
1.) Pulmonary Vascular Disease Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.
2.) Lung inflammation and regeneration (stem cells)
3.) Lung surfactant rheology and oxidative stress
4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms -
Pankaj Kapahi
Professor (Research) of Medicine (Endocrinology)
BioPankaj Kapahi is a Professor and aging researcher whose laboratory seeks to understand why organisms age and why the rate and consequences of aging differ so dramatically between individuals, sexes, and species. The lab approaches aging through the lens of evolution, asking how pathways that evolved to optimize growth, reproduction, and survival early in life can shape health and disease later in life.
A major focus of the laboratory is the interaction between nutrition, metabolism, reproduction, and aging. The lab has helped define how nutrient-sensing pathways, including TOR, dietary restriction, circadian biology, and metabolic adaptation regulate lifespan and age-related disease. More recently, this work has expanded to reproductive aging and the Reproductive Resilience Hypothesis, the idea that evolutionary pressures linking reproductive success to prolonged survival, repeated reproduction, and caregiving may have selected for biological programs that simultaneously support reproduction and somatic resilience.
Using comparative and experimental approaches across flies, worms, mice, and humans, the lab studies how these evolutionarily conserved programs influence brain aging, neurodegeneration, metabolic disease, reproductive aging, cell senescence, and resilience. The broader philosophy of the laboratory is that aging is best understood not as an isolated biological program, but as an emergent consequence of the evolutionary trade-offs among reproduction, nutrition, growth, maintenance, and survival. -
Michael S. Kapiloff, MD, PhD
Reinhard Family Professor, Professor (Research) of Ophthalmology and, by courtesy, of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsDr. Michael S. Kapiloff is a faculty member in the Departments of Ophthalmology and Medicine (Cardiovascular Medicine) and a member of the Stanford Cardiovascular Institute. Although Dr. Kapiloff was at one time a Board-Certified General Pediatrician, he is currently involved in full-time basic science and translational research. His laboratory studies the basic molecular mechanisms underlying the response of the retinal ganglion cell and cardiac myocyte to disease. The longstanding interest of his laboratory is the role in intracellular signal transduction of multimolecular complexes organized by scaffold proteins. Recently, his lab has also been involved in the translation of these concepts into new therapies, including the development of new AAV gene therapy biologics for the prevention and treatment of heart failure and for neuroprotection in the eye.
URL to NCBI listing of all published works:
http://www.ncbi.nlm.nih.gov/sites/myncbi/michael.kapiloff.1/bibliography/40252285/public/?sort=date&direction=descending
For more information see Dr. Kapiloff's lab website: http://med.stanford.edu/kapilofflab.html -
Katherine Kaplan
Clinical Associate Professor, Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsDr. Kaplan's research interests span four (often overlapping) domains: (1) pathophysiologic aspects of insomnia and hypersomnia in mood disorders, including mechanisms, correlates, and sequelae of these sleep disturbances; (2) behavioral interventions for sleep disturbances in adults and adolescents; (3) circadian and psychosocial factors impacting sleep in adolescence; and (4) machine learning approaches to big data.
