School of Medicine
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Professor of Medicine (Cardiovascular Medicine)
BioClinical Focus: Cardiovascular Medicine: Atrial Fibrillation; Chronic CAD; ACS;
My primary research interest is the design and conduct of multicenter clinical trials and analyses of important clinical cardiac issues using large patient databases. My research focuses on novel anticoagulation agents for the treatment of acute coronary syndromes and atrial fibrillation, the study of agents targeted to protect the myocardium during reperfusion therapy for acute myocardial infarction, and the evaluation of cardiovascular safety of diabetic therapies. I am also interested in the methodology of clinical trials. Current research activities include standardization of the definition of myocardial infarction used in clinical trials, the adjudication of suspected clinical endpoint events by Clinical Event Committees (CEC), and the efficient operational conduct of large multinational clinical trials.
Administrative Focus: Associate Dean, Clinical Research School of Medicine; Vice Chair of Clinical Research Department of Medicine; Director Stanford Center for Clinical Research; Member of the Stanford IRB
1985 Stanford University, BS Chemistry
1989 University of Washington, MD
1993 University of Arizona, Internship/Residency/Chief Residency
1996 Duke University, Fellowship in Cardiology
1996 Duke University, Faculty in Cardiology
2013 Stanford University, Faculty Cardiovascular Medicine
Antonio Meola, MD, PhD
BioAntonio Meola M.D. Ph.D graduated Summa cum Laude and Research Honors at the University of Pisa, Italy, in 2008, and completed his residency training in Neurosurgery at the same Institution in July 2015. Dr Meola attended a Ph.D. program at the University of Florence, Italy, where he discussed a doctoral thesis entitled "A New Head-Mounted Display-based Augmented Reality System in Neurosurgical Oncology: a study on phantom".
Since 2/2014 to 1/2015 Dr Meola completed a Research Fellowship in Neurosurgical anatomy at the University of Pittsburgh Medical Center (UPMC), under the Direction of Dr. Juan C. Fernandez-Miranda. The main focus of his research was the surgical neuroanatomy of the white matter tracts of the human brain.
Since 7/2015 to 6/2016 Dr Meola served as Clinical Fellow in Image-Guided Neurosurgery at the Brigham and Women's Hospital, Harvard Medical School, in Boston, MA (Director: Dr. Alexandra J. Golby M.D.). During the fellowship, he focused on the clinical application and integration of advanced imaging techniques, including intraoperative-MRI, intraoperative US, functional MRI, tractography.
Since 7/2016 to 6/2017 Dr Meola completed a Neurosurgical Oncology Fellowship at the Cleveland Clinic in Cleveland, OH, devoting his efforts to minimally-invasive neurosurgical techniques, such as Laser interstitial Thermal Therapy (LITT) and stereotactic radiosurgery (Gamma Knife), as well as to awake neurosurgery.
Starting 7/2017, Dr Meola joined the Department of Neurosurgery at Stanford. Dr. Meola mainly focuses on conventional and innovative treatments for brain and skull base tumors, including both surgery and stereotactic radiosurgery (CyberKnife).
Professor of Pediatrics (Pulmonary Medicine) and, by courtesy, of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsAt Stanford University I developed and currently direct the CF Translational Research Center. The overarching goal of the center is to provide the groundwork to streamline, accelerate, and promote the translation of basic discoveries into effective therapies and interventions to benefit patients affected by cystic fibrosis. My laboratory group currently has three main lines of investigation: respiratory cell biology in CF; remote biochemical monitoring; and lung physiology in young children.
George D. Smith Professor of Translational Medicine
Current Research and Scholarly InterestsTwo areas: 1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling. Focus: protein kinase C in heart and large GTPases regulating mitochondrial dynamics in neurodegdenration. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, and glucose-6-phoshate dehydrogenase, in normal cells and in models of human diseases.