School of Medicine
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Emmanuel Mignot, MD, PhD
Craig Reynolds Professor of Sleep Medicine and Professor, by courtesy, of Genetics and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsThe research focus of the laboratory is the study of sleep and sleep disorders such as narcolepsy and Kleine Levin syndrome. We also study the neurobiological and genetic basis of the EEG and develop new tools to study sleep using nocturnal polysomnography. Approaches mostly involve human genetic studies (GWAS, sequencing), EEG signal analysis (deep learning), and immunology (narcolepsy is an autoimmune disease of the brain). We also work on autoimmune encephalitis.
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Pardis Miri
Basic Life Research Scientist, Genetics
BioPardis Miri, PhD, is a Research Scientist and former Postdoctoral Fellow at Stanford University, where she develops technology aimed at improving mental well-being. She holds a PhD in Computer Science and has extensive training in affective science under Professor James J. Gross. Pardis leads a multidisciplinary team (http://wehab.stanford.edu
) conducting clinical and real-world studies to assess how wearable technologies can reduce stress and enhance glymphatic flow in early-stage Alzheimer’s patients.
During her postdoctoral work, Pardis served as the principal investigator of FAR, a multi-disciplinary project to design, build, and evaluate an end-to-end wearable system for children with emotion dysregulation, including those diagnosed with autism spectrum disorder. FAR aims to support more adaptive emotion-regulation strategies through a combination of systems design and behavioral research.
Pardis is advised by Professors Michael Snyder, Keith Marzullo, and James J. Gross, and collaborates with Professor Antonio Hardan of the Stanford School of Medicine on research involving children with autism spectrum disorder.