School of Medicine


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  • Nicholas Harlan Smith

    Nicholas Harlan Smith

    Bioinformatician/Research Data Analyst, Stanford Cancer Institute Core

    BioI am a bioinformatician with over 10 years experience working with genomics and transcriptomic data. I studied at UC San Diego graduating in 2014 before moving to Germany in 2018 to get my master's degree in Informatiks (Computer Science). I wrote my master's thesis on utilizing RNA-seq data to identify genomic variants that can be used to aid diagnostics in rare diseases. After 5 years in Germany, I returned to California and started working in the Curtis Lab as a bioinformatician primarily with breast cancer data.

  • David Solow-Cordero

    David Solow-Cordero

    Associate Director, High-Throughput Screening, Innovative Medicines Accelerator (IMA)

    Current Role at StanfordAssociate Director, High-Throughput Screening Knowledge Center, , Sarafan ChEM-H and Innovative Medicine Accelerator (IMA)

    This high-throughput screening (HTS) laboratory allows Stanford researchers and others to discover novel modulators of targets that otherwise would not be practical in industry. The center incorporates instrumentation (purchased with NCRR NIH Instrumentation grant numbers S10RR019513, S10RR026338, S10OD025004, and S10OD026899), databases, compound libraries, and personnel whose previous sole domains were in industry.

    Among our instrumentation are a fully automated Molecular Devices ImageXpress Micro Confocal High-Content fluorescence microplate imager, with live cell, fluidics and phase contrast options, an Echo 655 Acoustic Dispense, a Thermo integrated HTS robotic system, a Caliper Life Sciences SciClone ALH3000 and an Agilent Bravo microplate liquid handler, and the BMG Clariostarplus, Tecan Infinite M1000 and M1000 PRO and Molecular Devices FlexStation II 384 fluorescence, luminescence and absorbance multimode microplate readers.

    We have over 180,000 small molecules for compound screens, 15,000 cDNAs for genomic screens, and whole genome siRNA libraries targeting the human genome (the siARRAY whole human genome siRNA library from Dharmacon, targeting 21,000 human genes) and the mouse genome (Qiagen mouse whole genome siRNA set V1 against 22,124 genes).

    The HTSKC main screening lab is located in ChEM-H W008, the cell-based assay development lab is located in CCSR Room 0133-North Wing, between the Transgenic Mouse Facility, and the Stanford Genomics Facility.