School of Medicine
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Alexander Isaac Salter
Affiliate, Department Funds
Fellow in Medicine - Med/HematologyBioI am a clinical fellow in medical oncology at Stanford University whose long-term goal is to become a translational physician-scientist who develops curative cellular immunotherapies for solid tumors. As a graduate student, I conducted the first comprehensive signaling analyses of therapeutically engineered T cells, demonstrating that signal strength, rather than quality, is a key determinant of T cell function and fate. These findings helped inform the design of next-generation cellular immunotherapies, some of which are now in clinical trials. I also co-led a collaboration with Dr. David Baker’s laboratory at the University of Washington to engineer synthetic protein “logic gates” enabling combinatorial antigen recognition with high precision, offering a potential path to more safely target solid tumors. My doctoral research resulted in 16 publications, including four prominent first-, co-first-, or second-author papers in high-impact journals, several reviews and textbook chapters, and recognition on the Forbes 30 Under 30 List.
At Stanford, I focus on translating cellular therapies for thoracic and genitourinary malignancies. Under the mentorship of Drs. Crystal Mackall and Allison Betof Warner, I am developing CAR T cells for lung cancer in non- and never-smokers and serve as a sub-investigator on an upcoming first-in-human phase 1 trial of drug-regulatable CAR T cells for adults with advanced solid tumors.
