School of Medicine

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  • Jou-Ho Shih

    Jou-Ho Shih

    Postdoctoral Scholar, Genetics

    Bio2011 B.S., Life Science, National Tsing Hwa University, Taiwan
    2019 Ph.D., Genome and Systems Biology Degree Program, National Taiwan University, Taiwan; Advisor: Dr. Yuh-Shan Jou
    2019-2020 Postdoctoral Fellow, Biomedical Science, Academia Sinica, Taiwan; Advisor: Dr. Yuh-Shan Jou
    2020-present Postdoctoral Fellow, Dept. Genetics, Stanford University, CA; Advisor: Dr. Michael Snyder

  • Mahasish Shome

    Mahasish Shome

    Postdoctoral Scholar, Genetics

    BioI am a postdoctoral fellow in Department of Genetics working in Dr. Michael Snyder’s lab. My research interest revolves around studying humoral immunity to understand disease pathology. I am currently working on Postacute sequelae of SARS-CoV-2 infection (PASC) patients who experienced various symptoms after COVID infection and vaccination. We looked into the antibody profile of this cohort and also the B cell receptor (BCR) repertoire for possible clonal expansion. We are specifically trying to understand if there is an autoimmune component leading to these symptoms observed in PASC cohort. We also plan to decipher the reason behind some individuals having symptoms after vaccination while others do not.
    I am also interested in inflammatory bowel disease pathology and how gut microbiome plays a role in disease progression. I am focusing on Adherent Invasive Escherichia Coli as a pathobiont microbe target.

  • Han Sun

    Han Sun

    Postdoctoral Scholar, Genetics
    Biostatistician 2, Pediatrics - Endocrinology

    BioHan had been a postdoc with Dr. Steinmetz at the genetics department for five years, working on both cancers and heart diseases, trying to understand the mechanisms linking from variants to disease phenotypes. This led to a few very interesting findings of aberrant splicing regulation, such as splicing-mediated readthrough stabilization (SRS), one more mechanism for oncogene activation in multiple types of cancers, and tissue-specific splicing of a mitochondrial inner membrane protein, suggesting a molecular connection between deficiency in energy-supplying and dilated cardiomyopathy.

    After being a senior computational biologist with Dr. Gloyn, who has been dedicated to the research of type 2 diabetes for decades, Han switched to the field of this multifactorial metabolic disease. It did take some courage to make such a switch at his post-postdoc stage, however, Han has a consistent interest in studying PG&E, which is not pacific gas and electric nearby, but the interaction between phenotype, genotype, and environment. With years of hands-on experience in statistical modeling and the analysis of next-generation sequencing and mass spectrometry data, in addition to a good understanding of disease genetics, cancer biology, and systems biology, Han is highly confident that he will enjoy the adventure and contribute to our understanding of diabetes.