School of Medicine


Showing 11-20 of 28 Results

  • Seth Lawrence Sherman, MD

    Seth Lawrence Sherman, MD

    Associate Professor of Orthopaedic Surgery

    Current Research and Scholarly InterestsMy research focuses on ways to augment tissue healing, improve human performance, and prevent musculoskeletal injuries. Approaching these challenges through parallel basic science and clinical pathways, our team works from the “bedside to the bench and back to the bedside”, identifying areas of clinical need to deliver evidence-based solutions for patients.

    We collaborates with orthopaedic surgeons, non-surgical physicians, and researchers within bioengineering, human performance, and musculoskeletal imaging across the Stanford campus. The team is developing novel methods to accurately record human movement (including wearable technology, phone-based systems), rapid MRI imaging protocols, and exploring the use of biomarkers to track injury and recovery. This research builds on my earlier work, which utilized portable, inexpensive software for Microsoft Kinect to detect knee injury risk in youth athletes performing a drop vertical jump test. The team’s multifaceted goal is: 1) develop innovative methods to screen for injury risk (i.e. youth athlete non-contact ACL), 2) create targeted intervention programs to reduce risk, 3) enhance athletic performance; and 4) improve accuracy of return to play testing following injury/surgery (i.e. clinical evaluation, biomarkers, functional tests, imaging analysis for healing).

    In the laboratory,our team investigates cellular and molecular deficiencies in tissue types including tendon, ligament, articular cartilage, and meniscus. By understanding aberrant pathways leading to tissue injury, they can identify innovative therapeutic targets for intervention. In collaboration with the Genetic Engineering and Synthetic Biology laboratories, Dr. Sherman’s research has explored the role of orthobiologic agents such as platelet rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) for tissue healing in patella tendinopathy (the breakdown of collagen in a tendon). Our lab is also investigating the use of CBD for musculoskeletal applications as an alternative to commonly used local anesthetics and cortisone derivatives. In my earlier work, we researched the cellular toxicity of such applications.

    In addition to basic science research, I have helped to build a Sports Medicine clinical research team that includes several full-time clinical research coordinators, residents, fellows, and students. The team collects prospective outcomes on their patients using a novel data collection platform called Patient IQ. The group is part of the JUPITER study which is the largest, multicenter study ever assembled in patellofemoral instability. They are additionally planning to enroll in FDA-approved clinical studies investigating pioneering strategies for knee cartilage restoration, joint preservation, and orthobiologic injections for osteoarthritis. Recent clinical publications explore outcomes in meniscus preservation and transplantation, medial patellofemoral ligament reconstruction, osteochondral allograft and matrix-induced autologous chondrocyte implantation (MACI), and surgical augmentation using PRP/BMAC. The clinical research team actively reports results of non-surgical and surgical interventions to continue to introduce new knowledge to the field, with the goal of improved patient outcome.

  • Vivian Shih, MD

    Vivian Shih, MD

    Clinical Associate Professor, Orthopaedic Surgery

    BioDr. Vivian Shih received her Bachelor of Science with honors and Doctor of Medicine degree from the University of Miami. In 2002, she completed her postgraduate medical training in Physical Medicine and Rehabilitation at the Feinberg School of Medicine at Northwestern University and the Rehabilitation Institute of Chicago (Shirley Ryan Ability Lab). She is board certified in Physical Medicine and Rehabilitation (PM&R or Physiatry) and specializes in non­-surgical management of musculoskeletal disorders, arthritis, gait and balance disorders. She also performs electrodiagnostic testing (EMG/NCS), ultrasound guided joint/soft tissue injections, and platelet rich plasma (PRP) injections. Dr. Shih previously practiced in the New Haven area from 2005 to 2018. She was an Attending Physician at Yale-New Haven Hospital and on faculty at the Yale School of Medicine. Prior to that, she had been practicing at Northwestern University Medical Center and the Rehabilitation Institute of Chicago. She has published in the Arthritis and Rheumatism journal, Academy of Physical Medicine & Rehabilitation (AAPM&R) online review, Archives of Physical Medicine and Rehabilitation journal, and Koopman's Arthritis and Allied Health textbook. She is a member of the AAPM&R, Association of Academic Physiatrists (AAP), and the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM).

  • Robert Lane Smith

    Robert Lane Smith

    Professor (Research) of Orthopedic Surgery, Emeritus

    Current Research and Scholarly InterestsOur group is interested in the molecular and cell biology underlying bone and cartilage metabolism in health and disease. Normal daily activities are linked to the ability of the articular cartilage to withstand normal joint forces that may reach 5-7 times body weight and bone homeostasis depends on daily mechanical loading histories.