School of Medicine
Showing 621-630 of 1,299 Results
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Gavin Sherlock
Professor of Genetics
Current Research and Scholarly InterestsEvolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species
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Seth Lawrence Sherman, MD
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsMy research focuses on ways to augment tissue healing, improve human performance, and prevent musculoskeletal injuries. Approaching these challenges through parallel basic science and clinical pathways, our team works from the “bedside to the bench and back to the bedside”, identifying areas of clinical need to deliver evidence-based solutions for patients.
We collaborates with orthopaedic surgeons, non-surgical physicians, and researchers within bioengineering, human performance, and musculoskeletal imaging across the Stanford campus. The team is developing novel methods to accurately record human movement (including wearable technology, phone-based systems), rapid MRI imaging protocols, and exploring the use of biomarkers to track injury and recovery. This research builds on my earlier work, which utilized portable, inexpensive software for Microsoft Kinect to detect knee injury risk in youth athletes performing a drop vertical jump test. The team’s multifaceted goal is: 1) develop innovative methods to screen for injury risk (i.e. youth athlete non-contact ACL), 2) create targeted intervention programs to reduce risk, 3) enhance athletic performance; and 4) improve accuracy of return to play testing following injury/surgery (i.e. clinical evaluation, biomarkers, functional tests, imaging analysis for healing).
In the laboratory,our team investigates cellular and molecular deficiencies in tissue types including tendon, ligament, articular cartilage, and meniscus. By understanding aberrant pathways leading to tissue injury, they can identify innovative therapeutic targets for intervention. In collaboration with the Genetic Engineering and Synthetic Biology laboratories, Dr. Sherman’s research has explored the role of orthobiologic agents such as platelet rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) for tissue healing in patella tendinopathy (the breakdown of collagen in a tendon). Our lab is also investigating the use of CBD for musculoskeletal applications as an alternative to commonly used local anesthetics and cortisone derivatives. In my earlier work, we researched the cellular toxicity of such applications.
In addition to basic science research, I have helped to build a Sports Medicine clinical research team that includes several full-time clinical research coordinators, residents, fellows, and students. The team collects prospective outcomes on their patients using a novel data collection platform called Patient IQ. The group is part of the JUPITER study which is the largest, multicenter study ever assembled in patellofemoral instability. They are additionally planning to enroll in FDA-approved clinical studies investigating pioneering strategies for knee cartilage restoration, joint preservation, and orthobiologic injections for osteoarthritis. Recent clinical publications explore outcomes in meniscus preservation and transplantation, medial patellofemoral ligament reconstruction, osteochondral allograft and matrix-induced autologous chondrocyte implantation (MACI), and surgical augmentation using PRP/BMAC. The clinical research team actively reports results of non-surgical and surgical interventions to continue to introduce new knowledge to the field, with the goal of improved patient outcome. -
Bansari Sureshchandra Sheth
Adjunct Clinical Assistant Professor, Medicine - Primary Care and Population Health
BioDr. Sheth is originally from southern California, but has progressively moved up the coast over the last few years, now making the Bay Area her wonderful new home. Board certified in Family Medicine, she had comprehensive training during residency. She has a variety of special interests, including pediatric illnesses, women’s health, diabetes care including lifestyle management, as well as Hepatitis C treatment. She believes in empowering her patients, working together with them as a team. In her free time, Dr. Sheth enjoys yoga, going to plays or musicals, comedy shows, and hiking.
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Kunj Sheth
Assistant Professor of Urology
BioDr. Kunj Sheth is a pediatric urologist who focuses on minimally-invasive approaches to children’s surgery and treatment of complex patients. She is currently in the Biodesign Faculty Fellows Program. Her research focuses on the design and development of health technology specifically for children. She is also working to improve surgical education for residents through 3-dimensional modeling for minimally-invasive surgery. She is a part of the UCSF-Stanford Pediatric Device Consortium. Kunj graduated from Northwestern University with an undergraduate degree in biomedical engineering. She attended Northwestern University Feinberg School of Medicine and completed a Urology residency training program at the University of Texas Southwestern Medical Center. She then completed a fellowship in Pediatric Urology at Baylor College of Medicine - Texas Children's Hospital.
