School of Medicine
Showing 921-930 of 1,295 Results
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David Solow-Cordero
Associate Director, High-Throughput Screening, Innovative Medicines Accelerator (IMA)
Current Role at StanfordAssociate Director, High-Throughput Screening Knowledge Center, , Sarafan ChEM-H and Innovative Medicine Accelerator (IMA)
This high-throughput screening (HTS) laboratory allows Stanford researchers and others to discover novel modulators of targets that otherwise would not be practical in industry. The center incorporates instrumentation (purchased with NCRR NIH Instrumentation grant numbers S10RR019513, S10RR026338, S10OD025004, and S10OD026899), databases, compound libraries, and personnel whose previous sole domains were in industry.
Among our instrumentation are a fully automated Molecular Devices ImageXpress Micro Confocal High-Content fluorescence microplate imager, with live cell, fluidics and phase contrast options, an Echo 655 Acoustic Dispense, a Thermo integrated HTS robotic system, a Caliper Life Sciences SciClone ALH3000 and an Agilent Bravo microplate liquid handler, and the BMG Clariostarplus, Tecan Infinite M1000 and M1000 PRO and Molecular Devices FlexStation II 384 fluorescence, luminescence and absorbance multimode microplate readers.
We have over 180,000 small molecules for compound screens, 15,000 cDNAs for genomic screens, and whole genome siRNA libraries targeting the human genome (the siARRAY whole human genome siRNA library from Dharmacon, targeting 21,000 human genes) and the mouse genome (Qiagen mouse whole genome siRNA set V1 against 22,124 genes).
The HTSKC main screening lab is located in ChEM-H W008, the cell-based assay development lab is located in CCSR Room 0133-North Wing, between the Transgenic Mouse Facility, and the Stanford Genomics Facility. -
Shamsi Soltani
Ph.D. Student in Epidemiology and Clinical Research, admitted Autumn 2021
BioShamsi Soltani is a PhD candidate in the Department of Epidemiology and Population Health and a trainee with the Center for Population Health Sciences, both in the Stanford School of Medicine. For three years, she was a fellow in the Training in Advanced Data Analytics for Behavioral and Social Sciences (TADA-BSSR) program, supervised by Drs. Abby King and Lorene Nelson. Her dissertation work revolves around modifiable risk factors for suicide in LGBTQ+ populations and is mentored by Dr. Mitchell Lunn.
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Ivan Soltesz
James R. Doty Professor of Neurosurgery and Neurosciences
BioIvan Soltesz received his doctorate in Budapest and conducted postdoctoral research at universities at Oxford, London, Stanford and Dallas. He established his laboratory at the University of California, Irvine, in 1995. He became full Professor in 2003, and served as department Chair from 2006 to July 2015. He returned to Stanford in 2015 as the James R. Doty Professor of Neurosurgery and Neurosciences at Stanford University School of Medicine. His major research interest is focused on neuronal microcircuits, network oscillations, cannabinoid signaling and the mechanistic bases of circuit dysfunction in epilepsy.
His laboratory employs a combination of closely integrated experimental and theoretical techniques, including closed-loop in vivo optogenetics, paired patch clamp recordings, in vivo electrophysiological recordings from identified interneurons in awake mice, 2-photon imaging, machine learning-aided 3D video analysis of behavior, video-EEG recordings, behavioral approaches, and large-scale computational modeling methods using supercomputers. He is the author of a book on GABAergic microcircuits (Diversity in the Neuronal Machine, Oxford University Press), and editor of a book on Computational Neuroscience in Epilepsy (Academic Press/Elsevier). He co-founded the first Gordon Research Conference on the Mechanisms of neuronal synchronization and epilepsy, and taught for five years in the Ion Channels Course at Cold Springs Harbor. He has over 30 years of research experience, with over 20 years as a faculty involved in the training of graduate students (total of 16, 6 of them MD/PhDs) and postdoctoral fellows (20), many of whom received fellowship awards, K99 grants, joined prestigious residency programs and became independent faculty. -
Scott G. Soltys, MD
Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy clinical and research interests focus on the development of new radiation techniques involving stereotactic radiosurgery and radiotherapy for the treatment of malignant and benign tumors of the brain and spine, as well as functional disorders such as trigeminal neuralgia.
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Hugh Brent Solvason PhD MD
Clinical Professor, Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsMy work is focused on novel interventional treatment approaches for treatment resistant unipolar and bipolar depression. We are currently enrolling patients with treatment refractory bipolar depression for a radiosurgical neuromodulation study. We are awaiting the start of enrollment for a DBS in unipolar depression study.
I am also working with children in Sub Saharan Africa. Primarily I am focused on methods to assess well-being, and long term outcomes for these vulnerable children. -
Sulaiman Somani
Clinical Scholar, Medicine
Resident in Med/Hospital MedicineCurrent Research and Scholarly InterestsSulaiman Somani is passionate about harnessing the power of cardiovascular signals (e.g., electrocardiograms) and large clinical data (e.g., unstructured like clinical notes) with artificial intelligence to create digital health tools to explain important research questions in and develop digital health tools for prevalent problems in Preventive Cardiology and Cardiac Electrophysiology, particularly around atrial fibrillation.
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Barbara Sommer
Associate Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center, Emerita
Current Research and Scholarly InterestsI am interested in the clinical investigation of cognitive stresses during younger adulthood that may give rise to frank intellectual impairment with older age. Examples may include specific kinds of chronically taken medications.
