School of Medicine
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Laurens van de Wiel
Postdoctoral Scholar, Cardiovascular Medicine
BioLaurens van de Wiel is Dutch scientist from Berghem, The Netherlands. Laurens spent his undergrad in Software Development (BSc, Avans Hogeschool ‘s-Hertogenbosch) and Computing Science (MSc, Radboud University Nijmegen). Laurens continued his career at a start-up, where he created large-scale, real-time analytical software. Laurens continued on his academic trajectory at the Radboudumc in Nijmegen, where he started his PhD in bioinformatics.
During his PhD, Laurens integrated genetic data with protein 3D structures and protein domains. He utilized the skills he obtained before setting out on his academic trajectory; building large-scale, robust, reliable software. Exemplified by the MetaDome Web server (https://stuart.radboudumc.nl/metadome/). During his PhD, he developed novel methodologies for the interpretation of genetic variants of unknown clinical significance and, by integrating structural and evolutionary biology with genomics, Laurens identified 36 novel disease-gene associations for developmental disorders. These discoveries enabled diagnosis for over 500 families worldwide.
Laurens’ areas of expertise are (bioinformatic) software development, data integration of genetic variation with other omics, and his research aims are:
1.) Lessons long-learned in computer science aid computational biology
2.) Multi-omic data integration allows the impact measurement of genetic variation
3.) Diagnosing undiagnosed disorders will uncover novel insights into biology.
4.) International and multidisciplinary collaborations are key in diagnosing rare disorders.
At Stanford University, under guidance of Dr. Matthew Wheeler, he is conducting his postdoctoral studies in line with his research aims. -
Anubodh Sunny Varshney
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
BioDr. Anubodh Sunny Varshney is a Clinical Assistant Professor and Associate Director of the fellowship program in the section of Advanced Heart Failure, Transplant Cardiology, and Mechanical Circulatory Support at Stanford. In addition to caring for patients with advanced heart disease, he is also an Investigator in the Cardiovascular Outcomes, Policy, & Implementation Research Group (https://www.copirgroup.com/) where he works to identify patient groups that have ongoing unmet medical needs, define benchmark outcomes that next generation therapies should improve upon, and understand factors that influence adoption of novel drug and device therapies.
Dr. Varshney earned a BS in biomedical engineering from Washington University in St. Louis and an MD from the University of Texas Southwestern Medical School. He completed residency in Internal Medicine and fellowship in Cardiovascular Medicine at Brigham & Women’s Hospital/Harvard Medical School and fellowship in Advanced Heart Failure, Transplant Cardiology, and Mechanical Circulatory Support at Stanford University.
Dr. Varshney also has experience advising multiple medical device, drug, and digital health start-ups and currently serves as a Venture Advisor at Broadview Ventures, a philanthropically-funded, mission-driven investment organization that invests in early-stage companies developing technologies that have the potential to improve outcomes for patients with cardiovascular disease or stroke.
