School of Medicine
Showing 41-50 of 268 Results
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Laura van Dam
Postdoctoral Scholar, Immunology and Rheumatology
BioI am both trained as a biomedical researcher and medical doctor in internal medicine and strive to close the gap between the clinic and fundamental sciences with translational research. My focus is to study the mechanisms of autoimmune diseases and to translate research insights into therapeutics targeting autoimmunity. I have received my PhD in 2022 in Leiden for studying neutrophil extracellular traps and autoreactive B cells in renal autoimmune diseases. My postdoctoral research project in the Robinson lab focuses on investigating the underlying molecular mechanisms of the pathogenesis of ANCA-associated vasculitis. I particularly aim to identify potential microbial triggers and molecular mimicry in ANCA-associated vasculitis, by characterizing the nasal microbiome and sequencing T cells and B cells of ANCA-associated vasculitis patients.
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Matt van de Rijn
Sabine Kohler, MD, Professor of Pathology, Emeritus
Current Research and Scholarly InterestsOur research focuses on molecular analysis of human soft tissue tumors (sarcomas) with an emphasis on leiomyosarcoma and desmoid tumors. In addition we study the role of macrophages in range of malignant tumors.
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Stephanie Van de Ven
Member, Stanford Cancer Institute
BioAs Deputy Director of the Canary Center at Stanford for Cancer Early Detection I broadly oversee its operations and research programs. The Canary Center is focused on developing in vitro and in vivo tools for early cancer detection and its research spans the areas of biomarker discovery, development of molecular imaging agents, development of new diagnostic and imaging devices, and mathematical modeling. In my position I facilitate the clinical translation of cancer diagnostic tools and I enable innovative interdisciplinary research. My research expertise includes leading phase I-II clinical trials to evaluate a newly developed optical breast imaging system in combination with a novel imaging agent. I gained valuable experience in clinical translation of medical devices and in testing new imaging agents for the first time in patients. My training as a Radiology resident was instrumental in my decision to focus on cancer early detection research, because it clearly confronted me with the problem that most cancer patients are being diagnosed too late. I expanded my knowledge on biomarker research by developing proteomics assays during my postdoctoral fellowship at Stanford, in conjunction with my continued work in optical and photoacoustic molecular imaging. In my current role, I work with the faculty of the Canary Center and the Molecular Imaging Program at Stanford, and am committed to advancing cancer research by applying my medical training, clinical knowledge, and research expertise to managing collaborative programs and contribute to the success of the Center and its faculty.
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Laurens van de Wiel
Postdoctoral Scholar, Cardiovascular Medicine
BioLaurens van de Wiel is Dutch scientist from Berghem, The Netherlands. Laurens spent his undergrad in Software Development (BSc, Avans Hogeschool ‘s-Hertogenbosch) and Computing Science (MSc, Radboud University Nijmegen). Laurens continued his career at a start-up, where he created large-scale, real-time analytical software. Laurens continued on his academic trajectory at the Radboudumc in Nijmegen, where he started his PhD in bioinformatics.
During his PhD, Laurens integrated genetic data with protein 3D structures and protein domains. He utilized the skills he obtained before setting out on his academic trajectory; building large-scale, robust, reliable software. Exemplified by the MetaDome Web server (https://stuart.radboudumc.nl/metadome/). During his PhD, he developed novel methodologies for the interpretation of genetic variants of unknown clinical significance and, by integrating structural and evolutionary biology with genomics, Laurens identified 36 novel disease-gene associations for developmental disorders. These discoveries enabled diagnosis for over 500 families worldwide.
Laurens’ areas of expertise are (bioinformatic) software development, data integration of genetic variation with other omics, and his research aims are:
1.) Lessons long-learned in computer science aid computational biology
2.) Multi-omic data integration allows the impact measurement of genetic variation
3.) Diagnosing undiagnosed disorders will uncover novel insights into biology.
4.) International and multidisciplinary collaborations are key in diagnosing rare disorders.
At Stanford University, under guidance of Dr. Matthew Wheeler, he is conducting his postdoctoral studies in line with his research aims.
