School of Medicine


Showing 51-60 of 95 Results

  • Anandi Krishnan

    Anandi Krishnan

    Affiliate, Institute for Immunity, Transplantation, and Infection Operations
    Visiting Scholar, Institute for Immunity, Transplantation, and Infection Operations

    BioDr. Krishnan is a translational scientist with experiences in engineering, biosciences, molecular genetics and hematology. Having recently completed her NIH clinical scientist career development award (NHGRI 1K08HG010061-01A1, 2018-24), and NIH-supported research re-entry (NCATS 3UL1TR001085-04S1, 2016-18), Anandi’s interests are in expanding our understanding of the multifaceted function of anucleate blood platelets and their parent megakaryocytes in human disease.

    Her current work, applying platelet transcriptome profiling and machine learning principles, aims to nominate novel clinically relevant strategies for personalized cancer and antiplatelet/antithrombotic therapy. Continued development of this research is likely to identify key mechanistic variables in platelet- and megakaryocyte-specific response to health and disease.

    Recent contributions in both computational and mechanistic components of platelet and blood research lay the groundwork for sustaining contributions to the field of hematology genomic medicine (e.g. Shen et al PMID 34755136, Seetharam et al PMID 36712071, Kelliher et al PMID 37961700, Thomas & Krishnan PMID 38175681, Abbonante et al PMID 38165147, Jutzi et al PMID 35763665, Campbell et al PMID 36194487). Anandi was also was one of the first non-MD PhD scientist to be awarded the NHGRI K08 Clinical Scientist Research Career Development Award, the HTRS Mid-Career Research Award, and the MPN Research Foundation Challenge Grant Award, reflecting her consistent efforts bridging basic and clinical disciplines.

    Select other recognitions include:
    Member, Editorial Board, Journal of Thrombosis and Haemostasis (2024-)
    Ad hoc Reviewer, NIH CSR Cancer and Hematological Disorders Study Section (2023, 24)
    Host Mentor, ISTH Training Fellowship, International Society for Thrombosis and Haemostasis (2023)
    Member, Minority Recruitment Initiatives Subcommittee, American Society of Hematology (2022-26)
    Team Science Leadership Program at Stanford Medicine (2022)
    Peer Mentor, Pathology Stanford Network for Advancement and Promotion (2021)
    Research Mentor, Meharry Medical College, Nashville, Meharry-Stanford initiative *mentee selected for oral presentation & won 2nd place at Meharry (2021)
    Thrombosis & Hemostasis Societies of North America Young Investigator Award (2020)
    Invited Member and Panelist, NSF RESET Conference (2020)
    Invited Member/Panelist, iRelaunch Return to Work Conference, Stanford Alumni Association (2018)
    Featured twice by NIH NCATS in the ‘Features & Briefs’ & ‘Diversity Awardee Profiles’ webpages (2017,18)

    Complete list of publications: https://pubmed.ncbi.nlm.nih.gov/?term=anandi+krishnan&sort_order=asc

  • Wanlu Liu

    Wanlu Liu

    Affiliate, Institute for Immunity, Transplantation, and Infection Operations
    Visiting Scholar, Institute for Immunity, Transplantation, and Infection Operations

    BioAcademic Appointments
    - Associate Professor, Zhejiang University
    - Visiting Scholar, Stanford University School of Medicine (Mark M. Davis Lab)

    Professional Education
    - Ph. D., UCLA, Molecular Biology/Bioinformatics (2018)
    - B.Med., Zhejiang University School of Medicine (2013)

    Selected Publications:
    - Ruonan Tian#, Zhejian Yu#, Ziwei Xue, Lize Wu, Jiaxin Wu, Shuo Cai, Bing Gao, Bing He, Yu Zhao, Jianhua Yao, Linrong Lu, Wanlu Liu*; Evaluation of T cell receptor construction methods from scRNA-seq data, Genomics Proteomics & Bioinformatics, 2025, 22(6), qzae086
    - Ziwei Xue#, Lize Wu#, Ruonan Tian, Bing Gao, Yu Zhao, Bing He, Di Sun, Bingkang Zhao, Yicheng Li, Kaixiang Zhu, Lie Wang, Jianhua Yao*, Wanlu Liu*, Linrong Lu*; Integrative Mapping of Human CD8+ T Cell in Inflammation and Cancer, Nature Methods, 2025, 22(2), 435-445
    - Jian Zhang#, Ruonan Tian#, Jie Yuan#, Zhang Siwen, Zhexu Chi, Weiwei Yu, Qianzhou Yu, Zhen Wang, Sheng Chen, Mobai Li, Dehang Yang, Tianyi Hu, Qiqi Deng, Xiaoyang Lu, Xue Zhang, Jia Liu, Wanlu Liu*, Di Wang*; A two-front nutrient supply environment fuels small intestinal physiology through differential regulation of nutrient absorption and host defense, Cell, 2024, 187(22), 6251-6271.
    - Yaqi Su, Zhejian Yu, Siqian Jin, Zhipeng Ai, Ruihong Yuan, Xinyi Chen, Ziwei Xue, Yixin Guo, Di Chen, Hongqing Liang, Zuozhu Liu, Wanlu Liu*; Comprehensive assessment of mRNA isoform detection methods for long-read sequencing data, Nature Communications, 2024, 15, 3972
    - Yixin Guo, Ziwei Xue, Meiting Gong, Siqian Jin, Xindi Wu, Wanlu Liu*; CRISPR-TE: a web-based tool to generate single guide RNAs targeting transposable elements, Mobile DNA, 2024, 14(1), 3
    - Xinyu Xiang#, Yu Tao#, Jonathan DiRusso, Fei-Man Hsu, Jinchun Zhang, Ziwei Xue, Julien Pontis, Didier Trono, Wanlu Liu*, Amander T. Clark*; Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections, Nature Communications, 2022
    - Lize Wu#, Ziwei Xue#, Siqian Jin, Jinchun Zhang, Yixin Guo, Yadan Bai, Xuexiao Jin, Chaochen Wang, Lie Wang, Zuozhu Liu, James Q. Wang, Linrong Lu*, Wanlu Liu*; huARdb: human Antigen Receptor database for interactive clonotype-transcriptome analysis at the single-cell level, Nucleic Acids Research, 2021, gkab857
    - Yixin Guo, Ziwei Xue, Ruihong Yuan, Jingyi Jessica Li, William A. Pastor, Wanlu Liu*; RAD: a web application to identify region associated differentially expressed genes, Bioinformatics, 2021, 37(17): 2741-2743.

  • XIAOHUA LUO

    XIAOHUA LUO

    Affiliate, Institute for Immunity, Transplantation, and Infection Operations
    Visiting Scholar, Institute for Immunity, Transplantation, and Infection Operations

    BioAcademic Appointments
    - Visiting Scholar, Stanford University School of Medicine (Holden Maecker Lab)
    - Chief Physician / Associate Professor / Associate Research Scientist, The First Affiliated Hospital of Chongqing Medical University

    Professional Education
    - Visiting Scholar, Karolinska Institutet (Per Ljungman & Markus Maeurer Lab) (2016)
    - Ph. D., Peking University Health Science Centre (2009)
    - B.Med., Tongji Medical College, Huazhong University of Science and Technology (2001)

    Selected Publications:
    - Luo XH*, Zhu Y, Duan XQ, Peng W, Pei CX, Yang L, Li Q, Zhao M, Wang L. Histone HIST1 genes and tumor-infiltrating lymphocytes in a child with γδ T cell acute lymphoblastic leukemia by single-cell sequencing. Journal of Leukocyte Biology. 2025 Apr;117(4):qiaf022.
    - Shui LP, Zhu Y, Duan XQ, Chen YT, Yang L, Tang XQ, Zhang HB, Xiao Q, Wang L, Liu L, Luo XH*. HBsAg (‐)/HBsAb (‐)/HBeAg (‐)/HBeAb (+)/HBcAb (+) predicts a high risk of hepatitis B reactivation in patients with B ‐ cell lymphoma receiving rituximab based immunochemotherapy. Journal of Medical Virology. 2023 Feb 3.
    - Luo XH*, Poiret T, Liu Z, Meng Q, Nagchowdhury A, Ljungman P. Different recovery patterns of CMV-specific and WT1-specific T cells in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: Impact of CMV infection and leukemia relapse. Frontiers in Immunology. 2022;13.
    - Luo XH*, Zhu Y, Chen YT, Shui LP, Liu L. CMV Infection and CMV-Specific Immune Reconstitution Following Haploidentical Stem Cell Transplantation: An Update. Frontiers in immunology. 2021;12.
    - Luo XH*, Meng Q, Liu Z, Paraschoudi G. Generation of high-affinity CMV-specific T cells for adoptive immunotherapy using IL-2, IL-15, and IL-21. Clinical Immunology. 2020 Aug 1;217:108456.
    - Li S, Huang J, Zhang YL, Zhu Y, An YF, Du J, Zhang ZL, Xia Y, Liu L, Wang L, Luo XH*. Wiskott- Aldrich syndrome protein may be critical for CD8+ T cell function following MCMV infection. Cellular immunology. 2019 Apr 1;338:43-50.
    - Luo XH, Meng Q, Rao M, Liu Z, Paraschoudi G, Dodoo E, Maeurer M. The impact of inflationary cytomegalovirus-specific memory T cells on anti-tumour immune responses in patients with cancer. Immunology. 2018 Nov;155(3):294-308.
    - Zhenjiang L, Rao M, Luo X, Valentini D, von Landenberg A, Meng Q, Sinclair G, Hoffmann N, Karbach J, Altmannsberger HM, Jäger E. Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme. EBioMedicine. 2018 Jul 1;33:49-56.
    - Liu Zhenjiang, Martin Rao, Xiaohua Luo, Elisabeth Sandberg, Jiri Bartek Jr, Esther Schoutrop, Anna von Landenberg, Qingda Meng, Davide Valentini, Thomas Poiret, Georges Sinclair, Inti- Harvey Peredo, Ernest Dodoo, and Markus Maeurer*. Mesothelin-specific Immune Responses Predict Survival of Patients With Brain Metastasis. EBioMedicine. 2017 Sep; 23: 20–24.
    - Liu Z, Poiret T, Persson O, Meng Q, Rane L, Bartek J, Karbach J, Altmannsberger HM, Illies C, Luo X, Harvey-Peredo I. NY-ESO-1-and survivin-specific T-cell responses in the peripheral blood from patients with glioma. Cancer Immunology, Immunotherapy. 2018 Feb 1;67(2):237- 46.
    - Liu Z, Meng Q, Bartek Jr J, Poiret T, Persson O, Rane L, Rangelova E, Illies C, Peredo IH, Luo X, Rao MV. Tumor-infiltrating lymphocytes (TILs) from patients with glioma. Oncoimmunology. 2017 Feb 1;6(2):e1252894.
    - XH Luo, XJ Huang*, KY Liu, LP Xu, DH Liu. Protective immunity transferred by infusion of CMV- specific CD8+ T cells within donor grafts: its associations with CMV reactivation following unmanipulated allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2010; 16(7):994-1004
    - XH Luo, YJ Chang, LP Xu, DH Liu, KY Liu, XJ Huang*. The impact of graft composition on clinical outcomes in unmanipulated HLA-mismatched/haploidentical haematopoietic SCT. Bone Marrow Transplant 2009; 43(1):29-36.