School of Medicine
Showing 61-70 of 101 Results
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Alisa Mueller, MD, PhD
Assistant Professor of Medicine (Immunology and Rheumatology)
BioDr. Mueller is an Assistant Professor in the Division of Immunology and Rheumatology. As a physician-scientist, she leads a research laboratory investigating mechanisms that drive stromal pathology in rheumatoid arthritis and other chronic inflammatory conditions. Utilizing innovative techniques in immunology, genomics, and regenerative medicine, she and her team aim to develop novel therapeutic approaches to combat autoimmune diseases.
Dr. Mueller earned her MD and PhD degrees at Stanford University as part of the Medical Scientist Training Program where she investigated mechanisms regulating a mesenchymal progenitor population in skeletal muscle that mediates both healthy tissue regeneration and pathologic fibrosis. During her training, she was awarded predoctoral grants from the NIH National Institute on Aging and the California Institute of Regenerative Medicine. Her studies culminated in a first-author publication in Nature and co-authorship on publications in Cell and Nature Communications. Subsequently, she pursued medicine residency and rheumatology fellowship at Brigham and Women’s Hospital and Harvard Medical School where she explored mechanisms driving synovial fibroblast pathogenicity in rheumatoid arthritis. Her work led to the identification of non-canonical Wnt signaling as a critical mediator of RA synovial fibroblast inflammatory activation as well as the development of functional genomic screens to elucidate a broad set of novel therapeutic targets in inflammatory fibroblasts. Moreover, she has also led high-dimensional immunoprofiling studies to reveal underlying immune aberrations in patients with systemic sclerosis and elucidate biologic mechanisms catalyzing disease in patients with longstanding immune-related disorders of unknown etiology in partnership with the Undiagnosed Diseases Network. During her fellowship and instructorship, she received a Distinguished Fellow Award from the American College of Rheumatology as well as grants including the NIH NIAMS Mentored Clinical Scientist Research Career Development Award (K08), Rheumatology Research Foundation Scientist Development Award with the Malawista Endowment Distinction, Hearst Young Investigator Award, and Innovation Evergreen Fund Award. Her work has resulted in co-first author publications in the Journal of Clinical Investigation, Cell Reports Medicine, and ACR Open Rheumatology as well as as co-authorship on publications in Lancet Rheumatology and the New England Journal of Medicine.
In addition to her scientific endeavors, Dr. Mueller is also dedicated to providing high quality clinical care and education. She serves as an attending physician specializing in rheumatology where she mentors trainees in outpatient and inpatient settings and provides educational lectures. With an interdisciplinary team, she developed an interactive medical case on neurologic manifestations of lupus which was published in the New England Journal of Medicine. She was awarded an Arnold Dunne Award for Compassion and Dedication to Patient Care at Brigham and Women’s Hospital. By pursuing basic and translational research alongside clinical care, Dr. Mueller and her team strive to uncover basic mechanisms regulating stromal biology in autoimmune and inflammatory disease development and to create diagnostic strategies and targeted therapeutics that will benefit patients who do not respond to conventional therapies. -
Quan Dong Nguyen, MD, MSc
Professor of Ophthalmology and, by courtesy, of Pediatrics and of Medicine (Immunology & Rheumatology)
Current Research and Scholarly InterestsWe have focused our research on the development of novel therapies and innovative assessment and diagnostic imaging technologies for retinal vascular and ocular inflammatory disorders, specifically diabetic retinopathy (DR), age-related macular degeneration (AMD) and uveitis. Building on our initial work describing the role of hypoxia and vascular endothelial growth factor (VEGF) in diabetic retinopathy (DR) and diabetic macular edema (DME), We have become interested in the biochemical mechanisms that would presumably lead to DME. During the past decade, our research has contributed to the body of evidences that defines the important role of anti-VEGF therapies in DME and AMD, as well as the role of the mTOR pathway and various interleukins in the pathogenesis of uveitis.
We have launched a productive and well-funded clinical research program while at the same time providing clinical care to patients with uveitis and retinal vascular diseases and fulfilling significant teaching and administrative assignments. We have established a number of key collaborators both within and outside the institutions. In addition, we have also established Center in Baltimore and now in Silicon Valley, which has excelled in conducting proof-of concept, early-phase multi-center clinical trials and studies, exploring the clinical disease manifestations and the efficacy of various pharmacologic agents in retinal, uveitic, and ocular inflammatory disorders. -
Mahesh Pandit
Postdoctoral Scholar, Immunology and Rheumatology
BioI have completed my PhD in Immunology from Yeungnam University, South Korea. I studied adaptive immune cells especially focusing T cells and its relation to autoimmunity and tumor. I worked on different conditional knockout mice to investigate the cellular mechanisms. Similarly, I worked on disease induced mice to study its preventive and therapeutic approaches. Currently, I am working on Translational immunology as a Postdoctoral Researcher at Stanford University department of Immunology and Rheumatology. I focus on Epstein-Barr Virus, B cells and its relation with various autoimmune diseases.
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Anna Postolova, MD, MPH
Affiliate, Medicine - Med/Immunology & Rheumatology
BioDr. Postolova is board certified in internal medicine, allergy/immunology, and rheumatology. She cares for patients of all ages with compromised immune systems or allergic conditions including eczema, hives, angioedema, food and drug allergy, allergic rhinitis, asthma, and chronic rhinosinusitis.
She has authored papers and spoken on care for patients with an overlap of autoimmunity and immunodeficiency and conditions like lupus, rheumatoid arthritis, myositis, vasculitis, granulomatous mastitis, and osteoarthritis.
As a native Russian speaker, Dr. Postolova is sensitive to the cultural differences of patients and their families.
